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Gelastic seizures: A case of lateral frontal lobe epilepsy and review of the literature
Epilepsy and Behavior, 06/24/09

Kovac S et al. - The authors describe a 40-year-old patient with gelastic seizures triggered by hand movement. Despite nonlesional magnetic resonance imaging (MRI), electroencephalography (EEG), functional magnetic resonance imaging (fMRI), and diffusion tensor imaging (DTI) are concordant with seizure onset in the right frontocentral area. Seizure semiology and EEG recordings imply involvement of mesial frontal structures remote from seizure initiation site. The authors reviewed all published cases on gelastic seizures of frontal lobe origin to find characteristic features...This case highlights the importance of complementary functional investigations in MRI-negative epilepsies.

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