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Karatas H et al. - Herein the authors describe two patients with SOD-plus syndrome characterized by SOD with epilepsy and multiple skeletal and central nervous system abnormalities. These two cases indicate that SOD results from disorders in multiple developmental stages. In addition, this is the first report of SOD-plus syndrome with mirror hand movements. Advances in neuroradiological evaluation techniques enable the detection of associated central nervous system abnormalities that can be special characteristics for the diagnosis of the spectrum of SOD-plus.

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