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Impulsive and compulsive behaviors in Parkinson's disease
Movement Disorders, 06/18/09
Evans AH et al. – A review of impulsive and compulsive behaviors in Parkinsons disease focuses on the phenomenology, epidemiology, and methods to identify and rate these disorders.
Methods- Review of impulsive and compulsive behaviors in Parkinsons disease
- Antiparkinson therapy can be the primary cause of a range of nonmotor symptoms
- Symptoms include set of complex disinhibitory psychomotor pathologies linked by repetitive, reward, or incentive-based nature
- Behaviors relate to aberrant or excessive dopamine receptor stimulation
- Behaviors: impulse control disorders (ICDs), punding, and dopamine dysregulation syndrome
- Common ICDs: pathological gambling, hypersexuality, compulsive eating, and compulsive buying
- Management of dopaminergic drug-related compulsive behaviors based on neurobiological substrate of these disorders
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Enhanced frontal function in Parkinson’s disease
Brain, 12/18/09
Hereditary spastic paraplegia caused by the PLP1 "rumpshaker mutation"
Journal of Neurology, Neurosurgery, and Psychiatry , 12/18/09
Impaired sensorimotor integration in focal hand dystonia patients in the absence of symptoms
Journal of Neurology, Neurosurgery, and Psychiatry , 12/18/09
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