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Reduction of Functional Brain Connectivity in Mild Traumatic Brain Injury during Working Memory
Journal of Neurotrauma, 06/15/09
Kumar S et al. - The authors found that the MTBI patients had impaired verbal and visuo-spatial working memory. The different stages of working memory were associated with poor intrahemispheric coherence in long-range (fronto-parietal) and mid-range (fronto-temporal and temporo-parietal) regions as well as poor interhemispheric coherence in the frontal and temporal regions in the MTBI patients. The deficit in coherence was present in theta, alpha, and beta frequency bands. However, the MTBI and the control group had comparable coherence values in intra- and inter-hemispheric regions during eyes closed rest. The authors suggest that the inter- and intra-hemispheric functional connectivity is impaired in MTBI during working memory performance.
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