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See Latest ArticlesAbsence of anti-aquaporin-4 antibodies in narcolepsy
Sleep and Biological Rhythms, 06/01/09
Tanaka S et al. - In this study, the authors screened for anti-AQP4 antibodies in sera from 251 patients with narcolepsy, 34 with other hypersomnias, and 200 healthy controls by using the radioligand binding assay method. A positive result for anti-AQP4 antibodies was found only in one healthy control subject. All the hypersomnia patients were negative for this antibody. These results indicated that anti-AQP4 antibody is not useful as a diagnostic marker for narcolepsy and other hypersomnias.
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