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See Latest ArticlesBrain insulin infusion does not augment the counterregulatory response to hypoglycemia or glucoprivation
Metabolism-Clinical and Experimental, 06/03/09
Ishihara KK et al. - Although insulin infusion acted to stimulate hypothalamic insulin signaling, neither intrahypothalamic nor intracerebroventricular insulin infusion augmented the counterregulatory response to hypoglycemia or to 2DG-induced glucoprivation. Therefore, it is proposed that the previously noted acute actions of insulin to augment the sympathoadrenal response to hypoglycemia are likely mediated via mechanisms exterior to the central nervous system.
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