Neurology Medical News about modifeid Atkins diet;seizure reduction

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Comparison of seizure reduction and serum fatty acid levels after receiving the ketogenic and modified Atkins diet
Seizure - European Journal of Epilepsy, 05/08/09

Porta N et al. – A decrease of serum arachidonic acid levels may play a role in the anticonvulsive effects of ketogenic diet (KD) or modified Atkins diet. The KD and modified Atkins diet led to seizure reduction in this small pilot series, with slightly better results after 3 mo with KD, but not after 6 mo.

Methods

Retrospective comparison of the KD and modified Atkins diet in 27 children
Assessment of serum long chain fatty acid profiles

Results

After 3 mo, on intent-to-treat analysis, KD was more successful: >50% seizure reduction in 11/17 (65%) with KD vs 2/10 (20%) with modified Atkins diet
After 6 mo, this difference was no longer significant: 7/17 (41%) vs 2/10 (20%)
Preventive effect of both diets on occurrence of status epilepticus
Significant decrease in serum arachidonic acid concentration after 1 and 3 mo of either diet for responders vs non-responders

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