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See Latest ArticlesRelative contribution of simple mutations vs. copy number variations in five Parkinson disease genes in the Belgian population
Human Mutation, 05/04/09
Nuytemans K et al. - The relative contribution of simple mutations and copy number variations (CNVs) in SNCA, PARK2, PINK1, PARK7, and LRRK2 to the genetic etiology of Parkinson disease (PD) is still unclear because most studies did not completely analyze each gene. The PARK2 and LRRK2 mutation frequencies in Belgian PD patients were similar to those reported in other studies. However, at this stage the true pathogenic nature of some heterozygous mutations in recessive genes remains elusive.
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