Neurology

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Radiation effects on the intima-media thickness of the common carotid artery in post-radiotherapy patients with head and neck malignancy
Postgraduate Medical Journal, 01/07/09

Shariat M et al. - Data implies that there is a measurable, significant increase in intima–media thickness (IMT) of the common carotid artery after radiotherapy for head and neck malignancy compared with non-irradiated matched controls.

• Aim was to investigate if radiotherapy to the carotid area has any effect on the IMT of the common carotid artery
• 13 pts; completed radiotherapy to the carotid region at least 1 yr previously underwent ultrasound of the carotid artery
• IMT measurements were compared with 13 healthy controls, matched for age, sex and race, w/o history of radiotherapy

• Irradiated subjects had larger IMT measurements vs non-irradiated subjects
• Difference was significant with a confidence interval of 95%

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