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Does lamotrigine use in pregnancy increase orofacial cleft risk relative to other malformations?
Neurology, 07/24/08
Dolk H et al. - The authors find no evidence of a specific increased risk of isolated orofacial clefts relative to other malformations due to lamotrigine (LTG) monotherapy. The study is not designed to assess whether there is a generalized increased risk of malformations with LTG exposure.
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