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Benera, D., et al. - Herpes simplex-1 (HSV-1) is a sporadic cause of viral encephalitis. We have previously demonstrated that corneal HSV inoculation markedly activates the hypothalamo-pituitary-adrenal (HPA) axis...The results suggest that HSV-1 induced GC resistance may be mediated by downregulation of GC receptors in hippocampal tissue. These results may clarify a mechanism responsible for GC resistance following immune challenges

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Today in CNS Infectious Disease...keeping you current

Dysregulated Epstein-Barr virus infection in patients with CIDP
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Influence of Malnutrition on the Course of Childhood Bacterial Meningitis
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