The emerging role of synaptic cell-adhesion pathways in the pathogenesis of autism spectrum disorders
Betancur C et al. - The findings provide insights into the pathogenesis of ASDs and enable the development of model systems with construct validity for specific causes of ASDs. In several neurodevelopmental disorders frequently associated with ASD, including fragile X syndrome, Rett syndrome and tuberous sclerosis, animal models have led to the development of new therapeutic approaches, giving rise to optimism with other causes of ASDs. [more...]
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