Comparison of sleep/wake parameters for self-monitoring bipolar disorder
Bauer M et al. - Self-monitoring of sleep duration is recommended for patients with bipolar disorder. Better understanding of the long sleep duration of euthymic patients is required. Methods- 101 adult outpatients receiving treatment as usual recorded mood, sleep and medications every day on a home computer for a mean of 265 ± 103 days.
- A daily time series of mood, sleep duration (sleep plus bedrest), sleep onset and sleep offset was constructed for each patient.
- After applying an ARIMA (0,1,1) filter, a cross correlation function was used to analyze the temporal relationship between the residuals for lags of ± 7 days.
Results- Less frequent significant correlations were found between a change in either sleep onset or sleep offset and mood, than between sleep duration and mood.
- Patients with a significant correlation between sleep duration and mood included 86% of those with a significant correlation between sleep onset or sleep offset and mood.
- Mean sleep duration when euthymic was long (? 8 h in 89% of patients, ? 9 h in 51% of patients).
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