Cognitive Impairment in Huntington Disease: Diagnosis and Treatment
Current Neurology and Neuroscience Reports, 08/26/2011
Paulsen JS – Cognitive decline is associated with biological markers such as brain atrophy, circulating levels of brain–derived neurotrophic factors, and insulin–like growth factor 1. Efforts are now underway to develop valid and reliable measures of cognition in the prodrome as well as in all stages of Huntington Disease so that clinical trials can be conducted using cognitive outcomes.







