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Clinical features of headache patients with fibromyalgia comorbidity
The Journal of Headache and Pain, 08/25/2011
de Tommaso M et al. – A phenotypic profile where headache frequency concurs with anxiety, sleep disturbance, and pericranial tenderness should be individuated to detect the development of diffuse pain in headache patients.
Methods- A consecutive sample of 1,123 patients was screened
- Frequency of fibromyalgia(FM) in main groups and types of primary headaches; discriminating factor for FM comorbidity derived from headache frequency and duration, age, anxiety, depression, headache disability, allodynia, pericranial tenderness, fatigue, quality of life and sleep, and probability of FM membership in groups; and types of primary headaches were assessed
- FM was present in 174 among a total of 889 included patients
- Prevailed in tension–type headache main group (35%, p < 0.0001) and chronic tension–type headache subtype (44.3%, p < 0.0001)
- Headache frequency, anxiety, pericranial tenderness, poor sleep quality, and physical disability were the best discriminating variables for FM comorbidity, with 81.2% sensitivity
- Patients presenting with chronic migraine and chronic tension–type headache had a higher probability of sharing the FM profile (Bonferroni test, p < 0.01)