What’s your first-line option for current Neurology information? MDLinx Neurology! Where else but MDLinx Neurology will you find subspecialty coverage of articles published on dementia, headache, movement disorders, neurologic oncology, neurosensory disorders, neurosurgery, pain medicine, pediatric neurology, sleep, spine and more? Also discover the latest clinical pearls from the Smartest Neurologist daily quiz competition and Neurology Physician Review. In less than five minutes a day, you can skim the summaries of pertinent articles within 24 hours of publication. Do you need the 2-minute update? Skip to the highlights from our physician editor, D. Scott Cunningham, MD, PhD, for the “can’t miss” summaries on hot topics in neurology and related subspecialties.
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1 Long-term outcomes after nonlesional extratemporal lobe epilepsy surgery JAMA Neurology, June 19, 2013 Clinical Article
2 GABAergic transmission in temporal lobe epilepsy: The role of neurosteroids Experimental Neurology, June 19, 2013 Review Article
3 Complications of acute stroke and the occurrence of early seizures Cerebrovascular Diseases, June 19, 2013 Clinical Article
4 Bioequivalent antiepileptic drug switching and the risk of seizure-related events Epilepsy Research, June 19, 2013 Clinical Article
5 A functional magnetic resonance imaging study mapping the episodic memory encoding network in temporal lobe epilepsy Brain, June 19, 2013 Review Article
6 Health-related quality of life before and after pediatric epilepsy surgery: The influence of seizure outcome on changes in physical functioning and social functioning Epilepsy & Behavior, June 19, 2013 Clinical Article
7 A novel pedigree with familial cortical myoclonic tremor and epilepsy (FCMTE): Clinical characterization, refinement of the FCMTE2 locus, and confirmation of a founder haplotype Epilepsia, June 19, 2013 Clinical Article
8 Profile of perampanel and its potential in the treatment of partial onset seizures Full Text Neuropsychiatric Disease and Treatment, June 19, 2013 Clinical Article
9 Predictors for relapse after antiepileptic drug withdrawal in seizure-free patients with epilepsy Journal of Clinical Neuroscience, June 19, 2013 Clinical Article
10 Visual cortex hyperexcitability in idiopathic generalized epilepsies with photosensitivity: A TMS pilot study Epilepsy & Behavior, June 19, 2013 Clinical Article
11 Blood levels of cytokines in children with idiopathic partial and generalized epilepsy Seizure - European Journal of Epilepsy, June 19, 2013 Clinical Article
12 Analyzing depression coping strategies of patients with epilepsy: A preliminary study Seizure - European Journal of Epilepsy, June 19, 2013 Clinical Article
13 The association between BsmI polymorphism and risk factors for atherosclerosis in patients with epilepsy taking valproate Seizure - European Journal of Epilepsy, June 19, 2013 Clinical Article
14 Trans-middle temporal gyrus selective amygdalohippocampectomy for medically intractable mesial temporal lobe epilepsy in adults: Seizure response rates, complications, and neuropsychological outcomes Epilepsy & Behavior, June 19, 2013 Clinical Article
15 Attention impairment in childhood absence epilepsy: An impulsivity problem Epilepsy & Behavior, June 19, 2013 Clinical Article
16 Psychopathological and peripheral levels of neurobiological correlates of obsessive compulsive symptoms in patients with epilepsy: A hospital-based study Epilepsy & Behavior, June 19, 2013 Clinical Article
17 Short-term efficacy and tolerability of rufinamide adjunctive therapy in children with refractory generalised epilepsy Epileptic Disorders, June 19, 2013 Clinical Article
18 Association between leisure time, physical activity, and mood disorder levels in individuals with epilepsy Epilepsy & Behavior, June 19, 2013 Clinical Article
19 Risk factors of recurrent seizure, co-morbidities, and mortality in new onset seizure in elderly Seizure - European Journal of Epilepsy, June 19, 2013 Clinical Article
20 Seizures and antiepileptic drugs in patients with spontaneous intracerebral hemorrhages Seizure - European Journal of Epilepsy, June 8, 2013 Clinical Article
21 Relations between epileptic seizures and headaches Seizure - European Journal of Epilepsy, June 8, 2013 Clinical Article
22 Super refractory status epilepticus: the development of a paradigm for critical care management Full Text Minerva Anestesiologica, June 8, 2013 Review Article
23 Treatment with group psychotherapy for chronic psychogenic nonepileptic seizures Epilepsy & Behavior, June 8, 2013 Clinical Article
24 Efficacy and safety of adjunctive perampanel for the treatment of refractory partial seizures: A pooled analysis of three phase III studies Epilepsia, June 8, 2013 Clinical Article
25 Incidence and predictors of late seizures in intracerebral hemorrhages Stroke, June 8, 2013 Clinical Article
26 SISCOM and FDG-PET in patients with non-lesional extratemporal epilepsy: correlation with intracranial EEG, histology, and seizure outcome Epileptic Disorders, June 8, 2013 Clinical Article
27 Acute neonatal encephalopathy and seizures recurrence: A combined aEEG/EEG study Seizure - European Journal of Epilepsy, June 8, 2013 Clinical Article
28 Bright light therapy for symptoms of anxiety and depression in focal epilepsy: randomised controlled trial The British Journal of Psychiatry, May 27, 2013 Clinical Article
29 Modified Atkins diet vs classic ketogenic formula in intractable epilepsy Acta Neurologica Scandinavica, May 27, 2013 Clinical Article
30 Epilepsy Associated with Systemic Autoimmune Disorders Full Text Epilepsy Currents, May 27, 2013 Clinical Article
31 Sodium valproate use is associated with reduced parietal lobe thickness and brain volume Neurology, May 27, 2013 Clinical Article
32 Diagnostic evaluation in patients with intractable epilepsy and normal findings on mri: a decision analysis and cost-effectiveness study American Journal of Neuroradiology, May 27, 2013 Clinical Article
33 Prediction of seizure likelihood with a long-term, implanted seizure advisory system in patients with drug-resistant epilepsy: a first-in-man study The Lancet Neurology, May 27, 2013 Clinical Article
34 The Diagnosis and Treatment of Attention Deficit Hyperactivity Disorder in Patients with Epilepsy Current Neurology and Neuroscience Reports, May 27, 2013 Clinical Article
35 Characteristics of headache in children with epilepsy Seizure - European Journal of Epilepsy, May 27, 2013 Clinical Article
36 Epilepsy in pregnancy Clinical Obstetrics and Gynecology, May 27, 2013 Clinical Article
37 Simultaneous EEG and fMRI recordings (EEG-fMRI) in children with epilepsy Epilepsia, May 27, 2013 Review Article
38 Valproate and Lamotrigine in pediatric patients with refractory epilepsy: after the first year Pediatric Neurology , May 27, 2013 Clinical Article
39 Effects of levetiracetam on mu rhythm in persons with epilepsy Journal of Clinical Neuroscience, May 15, 2013 Clinical Article
40 Prognostic Importance of Risk Factors for Temporal Lobe Epilepsy in Patients Undergoing Surgical Treatment Mayo Clinic Proceedings, May 15, 2013 Clinical Article
41 Role of Reflexology and Antiepileptic Drugs in Managing Intractable Epilepsy - a Randomized Controlled Trial Research in Complementary Medicine, May 15, 2013 Clinical Article
42 Ictal-onset localization through connectivity analysis of intracranial EEG signals in patients with refractory epilepsy Epilepsia, May 15, 2013 Clinical Article
43 From Acupuncture to Interaction between -Opioid Receptors and Na+ Channels: A Potential Pathway to Inhibit Epileptic Hyperexcitability Full Text Evidence-based Complementary and Alternative Medicine , May 15, 2013 Review Article
44 Treatments for patients with comorbid epilepsy and depression: A systematic literature review Epilepsy & Behavior, May 15, 2013 Clinical Article
45 Incidence and prevalence of treated epilepsy among poor health and low-income Americans Neurology, May 15, 2013 Clinical Article
46 Diagnostic decision-making after a first and recurrent seizure in adults Seizure - European Journal of Epilepsy, May 15, 2013 Clinical Article
47 What predicts enduring intractability in children who appear medically intractable in the first 2 years after diagnosis Epilepsia, May 15, 2013 Review Article
48 Calcium antagonists as an add-on therapy for drug-resistant epilepsy Cochrane Reviews, May 4, 2013 Review Article
49 Intravenous topiramate: Safety and pharmacokinetics following a single dose in patients with epilepsy or migraines taking oral topiramate Epilepsia, May 4, 2013 Clinical Article
50 Pregnancy outcomes following gabapentin use: Results of a prospective comparative cohort study Neurology, May 4, 2013 Clinical Article
51 Neurological adverse events of new generation sodium blocker antiepileptic drugs. Meta-analysis of randomized, double-blinded studies with eslicarbazepine acetate, lacosamide and oxcarbazepine Seizure - European Journal of Epilepsy, May 4, 2013 Evidence Based Medicine Clinical Article
52 Effect of switching hepatic enzyme-inducer antiepileptic drug to levetiracetam on bone mineral density, 25 hydroxyvitamin D, and parathyroid hormone in young adult patients with epilepsy Epilepsia, May 4, 2013 Clinical Article
53 Pregnancy outcome in women exposed to antiepileptic drugs: teratogenic role of maternal epilepsy and its pharmacologic treatment Reproductive Toxicology, May 4, 2013 Clinical Article
54
Prevalence and subtypes of radiological cerebrovascular disease in late-onset isolated seizures and epilepsy
Clinical Neurology and Neurosurgery, May 4, 2013
Clinical Article
Exclusive Author Commentary
55 Impulsivity and seizure frequency, but not cognitive deficits, impact social adjustment in patients with juvenile myoclonic epilepsy Epilepsia, May 4, 2013 Clinical Article
56 Central sleep apnea and complex sleep apnea in patients with epilepsy Sleep and Breathing, May 4, 2013 Clinical Article
57 Coexistence of epilepsy and Brugada syndrome in a family with SCN5A mutation Epilepsy Research, May 4, 2013 Review Article
58 Early seizures after clipping of unruptured aneurysms of the anterior circulation: analysis on consecutive 1,000 cases Neurosurgical Review, April 23, 2013 Clinical Article
59 Young adult ischaemic stroke related acute symptomatic and late seizures: risk factors European Journal of Neurology, April 23, 2013 Clinical Article
60 Tiagabine-induced stupor in patients with psychogenic nonepileptic seizures: Nonconvulsive status epilepticus or encephalopathy Epilepsy & Behavior, April 23, 2013 Clinical Article
61 Electrode location and clinical outcome in hippocampal electrical stimulation for mesial temporal lobe epilepsy Seizure - European Journal of Epilepsy, April 23, 2013 Clinical Article
62 Patterns of cortical hyperexcitability in adolescent/adult-onset generalized epilepsies Epilepsia, April 23, 2013 Clinical Article
63 Network-specific mechanisms may explain the paradoxical effects of carbamazepine and phenytoin Epilepsia, April 23, 2013 Clinical Article
64 Changing trends in the use of seizure prophylaxis after traumatic brain injury: A shift from phenytoin to levetiracetam Journal of Critical Care, April 11, 2013 Clinical Article
65 Early developmental outcomes in children following convulsive status epilepticus: A longitudinal study Epilepsia, April 11, 2013 Clinical Article
66 ADORA2A polymorphism predisposes children to encephalopathy with febrile status epilepticus Neurology, April 11, 2013 Clinical Article
67
The value of repeat neuroimaging for epilepsy at a tertiary referral centre: 16 years of experience
Epilepsy Research, April 11, 2013
Clinical Article
Exclusive Author Commentary
In a study involving 87,025 postmenopausal women in the Women’s Health Initiative Observational Study, there were 1049 incident cases of ischemic stroke over 663,041 person-years of follow-up. Women in the highest quintile of trans fat intake were at increased risk of ischemic stroke (HR = 1.39) compared with women in the lowest quintile of trans fat intake. Aspirin use modulated the effect of trans fats; ASA users and ASA non-users had HRs for ischemic stroke of 0.95 and 1.66, respectively. Saturated, monounsaturated, and polyunsaturated fat intake were not associated with ischemic stroke.
Read the article summaryAs published in the Journal of Neurological Sciences, increase tea consumption (> 4 cups/d), and diet consisting of hot and spicy foods, and weight gain increase the likelihood of chronicity in patients with episodic migraines. During a 12-month prospective study involving 188 patients with episodic migraines, 17.7% developed chronic, daily migraines. Other risk factors included low education, a high frequency of headaches, headaches of long duration, allodynia, and increased symptomatic treatment of headaches.
Read the article summaryIn a randomized, double-blind, placebo-controlled trial, the calcium channel antagonist, ginsenoside-Rd, has been shown to improve functional outcomes in patients (n=386) with acute ischemic strokes. The patients received a 14-day infusion of ginsenoside-Rd within 72 hours of stroke onset. The National Institutes of Health Stroke Score was improved at 15 days and the modified Rankin score was improved at 90 days (OR = 1.74).
Read the article summary1 Aspirin nonresponders in patients with ischaemic stroke Blood Coagulation & Fibrinolysis, May 14, 2013
2 Effect of addition of clopidogrel to aspirin on stroke incidence: Meta-analysis of randomized trials International Journal of Stroke, May 23, 2013
3 Triple therapy with deferiprone, idebenone and riboflavin in Friedreich's ataxia – open-label trial Acta Neurologica Scandinavica, May 17, 2013
4 Treatment with statins and ischemic stroke severity Neurology, April 25, 2013
5 Effectiveness of antidementia drugs in delaying Alzheimers disease progression Alzheimer's & Dementia, May 2, 2013
6 Targeted use of heparin, heparinoids, or low-molecular-weight heparin to improve outcome after acute ischaemic stroke: an individual patient data meta-analysis of randomised controlled trials The Lancet Neurology, May 17, 2013 Evidence Based Medicine Review Article
7 Oxcarbazepine for neuropathic pain Cochrane Reviews, April 2, 2013 Review Article
8 The relationship between serum levels of vitamin D and migraine Journal of Research in Medical Sciences, March 12, 2013 Evidence Based Medicine
9 Cost-effectiveness of apixaban, dabigatran, rivaroxaban, and warfarin for stroke prevention in atrial fibrillation Stroke, May 29, 2013
10 Potential impact of new oral anticoagulants on the management of atrial fibrillation-related stroke in primary care International Journal of Clinical Practice, May 7, 2013
11 Operative mortality and stroke after on-pump vs off-pump surgery in high-risk patients: an analysis of 83 914 coronary bypass operations European Journal of Cardio-Thoracic Surgery, May 20, 2013
12 New Evidence for Therapies in Stroke Rehabilitation Current Atherosclerosis Reports, May 3, 2013 Evidence Based Medicine Review Article
13 The effects of long-term interferon- beta-1b treatment on cognitive functioning in multiple sclerosis: a 16-year longitudinal study Multiple Sclerosis Journal, May 10, 2013
14 Headaches during pregnancy Clinical Obstetrics and Gynecology, May 8, 2013
15 Atrial fibrillation in young stroke patients European Journal of Neurology, May 22, 2013
16 Aspirin with or without an antiemetic for acute migraine headaches in adults Cochrane Reviews, May 10, 2013 Evidence Based Medicine
17 Benefits of combined cholinesterase inhibitor and memantine treatment in moderate-severe Alzheimers disease Alzheimer's & Dementia, May 13, 2013 Review Article
18 Paracetamol (Acetaminophen) in stroke 2 (PAIS 2): Protocol for a randomized, placebo-controlled, double-blind clinical trial to assess the effect of high-dose paracetamol on functional outcome in patients with acute stroke and a body temperature of 36·5°C or above International Journal of Stroke, May 28, 2013
19 Inhaled Sevoflurane May Promote Progression of Amnestic Mild Cognitive Impairment: A Prospective, Randomized Parallel-Group Study The American Journal of the Medical Sciences, April 23, 2013
20 Dietary calcium intake and risk of stroke: a dose-response meta-analysis American Journal of Clinical Nutrition, April 5, 2013 Evidence Based Medicine
Indexed Journals in Neurology: Current Opinion in Neurology, Stroke, Seizure, Cephalgia, Brain Injury more
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