What’s your first-line option for current Neurology information? MDLinx Neurology! Where else but MDLinx Neurology will you find subspecialty coverage of articles published on dementia, headache, movement disorders, neurologic oncology, neurosensory disorders, neurosurgery, pain medicine, pediatric neurology, sleep, spine and more? Also discover the latest clinical pearls from the Smartest Neurologist daily quiz competition and Neurology Physician Review. In less than five minutes a day, you can skim the summaries of pertinent articles within 24 hours of publication. Do you need the 2-minute update? Skip to the highlights from our physician editor, D. Scott Cunningham, MD, PhD, for the “can’t miss” summaries on hot topics in neurology and related subspecialties.
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1 Optic Glioma in Children: A Retrospective Analysis of 101 Cases American Journal of Clinical Oncology, June 18, 2013 Clinical Article
2 International Pediatric Multiple Sclerosis Study Group criteria for pediatric multiple sclerosis and immune-mediated central nervous system demyelinating disorders: revisions to the 2007 definitions Multiple Sclerosis Journal, June 18, 2013 Clinical Article
3 Single priming dose of meningococcal group C conjugate vaccine (NeisVac-C) in infants Vaccine , June 18, 2013 Clinical Article
4 Extradural Hematoma in Children: Case Series of 33 Patients Pediatric Neurosurgery, June 18, 2013 Clinical Article
5 Is therapeutic hypothermia beneficial for pediatric patients with traumatic brain injury? A meta-analysis Child's Nervous System, June 18, 2013 Evidence Based Medicine Review Article
6 Risk Factors for Pediatric Arachnoid Cyst Rupture/Hemorrhage: A Case-Control Study Neurosurgery, June 18, 2013 Clinical Article
7 Histologic grade and extent of resection are associated with survival in pediatric spinal cord ependymomas Child's Nervous System, June 18, 2013 Review Article
8 ADAR2 editing activity in newly diagnosed versus relapsed pediatric high-grade astrocytomas Full Text BMC Cancer, June 18, 2013 Clinical Article
9 Phase I trial, pharmacokinetics, and pharmacodynamics of vandetanib and dasatinib in children with newly diagnosed diffuse intrinsic pontine glioma Clinical Cancer Research, June 18, 2013 Clinical Article
10 Phase I study of temozolomide combined with oral etoposide in children with malignant glial tumors Journal of Neuro-Oncology, June 18, 2013 Clinical Article
11 Intensity-modulated radiotherapy (IMRT) in pediatric low-grade glioma Cancer, June 7, 2013 Clinical Article
12 The molecular and cell biology of pediatric low-grade gliomas Oncogene, June 7, 2013 Review Article Clinical Article
13 Tumor origin and growth pattern at diagnosis and surgical hypothalamic damage predict obesity in pediatric craniopharyngioma Journal of Neuro-Oncology, June 7, 2013 Clinical Article
14 Epilepsy in a large cohort of children diagnosed with attention deficit/hyperactivity disorders (ADHD) Seizure - European Journal of Epilepsy, June 7, 2013 Clinical Article
15 Cerebral Venous Sinus Thrombosis in Pediatric Cancer Patients: Long-term Neurological Outcomes Journal of Pediatric Hematology/Oncology, June 7, 2013 Clinical Article
16 Autologous Tumor Lysate-pulsed Dendritic Cell Immunotherapy for Pediatric Patients with Newly Diagnosed or Recurrent High-grade Gliomas Anticancer Research, June 7, 2013 Clinical Article
17 Hypothermia Decreases Cerebrospinal Fluid Asymmetric Dimethylarginine Levels in Children With Traumatic Brain Injury Pediatric Critical Care, June 7, 2013 Clinical Article
18 Clinical Factors Associated With Invasive Testing and Imaging in Patients With Complex Febrile Seizures Pediatric Emergency Care, June 7, 2013 Review Article
19 Developmental dyslexia and vision Full Text Clinical Ophthalmology, June 7, 2013 Review Article Clinical Article
20 Vagal nerve stimulation in children under 12 years old with medically intractable epilepsy Child's Nervous System, June 7, 2013 Clinical Article
21 Treatment With Topotecan Plus Cyclophosphamide in Children With First Relapse of Neuroblastoma Pediatric Blood & Cancer, June 7, 2013 Clinical Article
22 Remission of benign epilepsy with rolandic spikes: An EEG-based connectivity study at the onset of the disease and at remission Epilepsy Research, June 7, 2013 Clinical Article
23 Comparison of hypothermia and normothermia after severe traumatic brain injury in children (Cool Kids): a phase 3, randomised controlled trial The Lancet Neurology, June 7, 2013 Clinical Article
24 Incidence, predictors and early post-operative course of diabetes insipidus in paediatric craniopharygioma: a comparison with adults Child's Nervous System, June 7, 2013 Clinical Article
25 Parental depression, maternal antidepressant use during pregnancy, and risk of autism spectrum disorders: population based case-control study Full Text British Medical Journal, May 14, 2013 Clinical Article
26 Transcranial Doppler Velocity and Brain MRI/MRA Changes in Children With Sickle Cell Anemia on Chronic Transfusions to Prevent Primary Stroke Pediatric Blood & Cancer, May 14, 2013 Clinical Article
27 The association of fetal cerebrovascular resistance with early neurodevelopment in single ventricle congenital heart disease American Heart Journal, May 14, 2013 Clinical Article
28 Autoimmune epilepsy in children: Case series and proposed guidelines for identification Epilepsia, May 14, 2013 Clinical Guideline Clinical Article
29 Acute seizures predict epilepsy after childhood stroke Annals of Neurology , May 14, 2013 Clinical Article
30 Neurodevelopmental Outcome in Extremely Preterm Infants at 2.5 Years After Active Perinatal Care in Sweden Neurodevelopmental Outcome in Extremely Preterm Infants JAMA, May 14, 2013 Clinical Article
31 Complications of epilepsy surgery--a systematic review of focal surgical resections and invasive EEG monitoring Epilepsia, May 14, 2013 Clinical Article
32 Can EEG characteristics predict development of epilepsy in autistic children European Journal of Paediatric Neurology, May 14, 2013 Clinical Article
33 Supra- and infratentorial pediatric ependymomas differ significantly in NeuN, p75 and GFAP expression Journal of Neuro-Oncology, May 14, 2013 Clinical Article
34 Effect of Topiramate Monotherapy on Height in Newly Diagnosed Children With Epilepsy Pediatric Neurology , May 3, 2013 Clinical Article
35 A new scoring system derived from platelet count and base deficit at presentation predicts mortality in paediatric meningococcal sepsis Critical Care, May 3, 2013 Clinical Article
36 FOXO3a Is a Major Target of Inactivation by PI3K/AKT Signaling in Aggressive Neuroblastoma Cancer Research, May 3, 2013 Clinical Article
37 EEG improvements with antiepileptic drug treatment can show a high correlation with behavioral recovery in children with ADHD Epilepsy & Behavior, May 3, 2013 Clinical Article
38 Treatment of electrographic seizures and status epilepticus in critically ill children: A single center experience Seizure - European Journal of Epilepsy, May 3, 2013 Clinical Article
39 Postconcussion Syndrome After Mild Traumatic Brain Injury in Children and Adolescents Requires Further Detailed Study Postconcussion Syndrome and Traumatic Brain Injury JAMA Neurology, April 22, 2013 Clinical Article
40 Comorbid anxiety and neurocognitive dysfunctions in children with ADHD European Child and Adolescent Psychiatry, April 22, 2013 Clinical Article
41 Pediatric Traumatic Brain Injury in 2012 Critical Care Clinics, April 21, 2013 Clinical Guideline
42 Cardiopulmonary complications during pediatric seizures: A prelude to understanding SUDEP Epilepsia, April 21, 2013 Clinical Article
43 Acute Encephalitis Critical Care Clinics, April 21, 2013 Review Article
44 Distinctive MRI Features of Pediatric Medulloblastoma Subtypes American Journal of Roentgenology, April 21, 2013 Review Article
45 Newly-diagnosed pediatric epilepsy is associated with elevated autoantibodies to glutamic acid decarboxylase but not cardiolipin Epilepsy Research, April 21, 2013 Clinical Article
46 Spinal Cord Compression in Childhood Pediatric Malignancies: Multicenter Egyptian Study Journal of Pediatric Hematology/Oncology, April 21, 2013 Clinical Article
47 Utility and safety of prolonged video-EEG monitoring in a tertiary pediatric epilepsy monitoring unit Epilepsy & Behavior, April 21, 2013 Clinical Article
48 Prognostic Factors and Survival Patterns in Pediatric Low-grade Gliomas Over 4 Decades Journal of Pediatric Hematology/Oncology, April 10, 2013 Clinical Article
49 Delayed Intracranial Hypertension and Cerebral Edema in Severe Pediatric Head Injury: Risk Factor Analysis Pediatric Neurosurgery, April 10, 2013 Clinical Article
50 Prolonged febrile seizures, clinical characteristics, and acute management Epilepsia, April 10, 2013 Clinical Article
51 Levetiracetam in children, adolescents and young adults with intractable epilepsy: Efficacy, tolerability and effect on electroencephalogram - A pilot study European Journal of Paediatric Neurology, April 10, 2013 Clinical Article
In a study involving 87,025 postmenopausal women in the Women’s Health Initiative Observational Study, there were 1049 incident cases of ischemic stroke over 663,041 person-years of follow-up. Women in the highest quintile of trans fat intake were at increased risk of ischemic stroke (HR = 1.39) compared with women in the lowest quintile of trans fat intake. Aspirin use modulated the effect of trans fats; ASA users and ASA non-users had HRs for ischemic stroke of 0.95 and 1.66, respectively. Saturated, monounsaturated, and polyunsaturated fat intake were not associated with ischemic stroke.
Read the article summaryAs published in the Journal of Neurological Sciences, increase tea consumption (> 4 cups/d), and diet consisting of hot and spicy foods, and weight gain increase the likelihood of chronicity in patients with episodic migraines. During a 12-month prospective study involving 188 patients with episodic migraines, 17.7% developed chronic, daily migraines. Other risk factors included low education, a high frequency of headaches, headaches of long duration, allodynia, and increased symptomatic treatment of headaches.
Read the article summaryIn a randomized, double-blind, placebo-controlled trial, the calcium channel antagonist, ginsenoside-Rd, has been shown to improve functional outcomes in patients (n=386) with acute ischemic strokes. The patients received a 14-day infusion of ginsenoside-Rd within 72 hours of stroke onset. The National Institutes of Health Stroke Score was improved at 15 days and the modified Rankin score was improved at 90 days (OR = 1.74).
Read the article summary1 Aspirin nonresponders in patients with ischaemic stroke Blood Coagulation & Fibrinolysis, May 14, 2013
2 Effect of addition of clopidogrel to aspirin on stroke incidence: Meta-analysis of randomized trials International Journal of Stroke, May 23, 2013
3 Triple therapy with deferiprone, idebenone and riboflavin in Friedreich's ataxia – open-label trial Acta Neurologica Scandinavica, May 17, 2013
4 Treatment with statins and ischemic stroke severity Neurology, April 25, 2013
5 Effectiveness of antidementia drugs in delaying Alzheimers disease progression Alzheimer's & Dementia, May 2, 2013
6 Targeted use of heparin, heparinoids, or low-molecular-weight heparin to improve outcome after acute ischaemic stroke: an individual patient data meta-analysis of randomised controlled trials The Lancet Neurology, May 17, 2013 Evidence Based Medicine Review Article
7 Oxcarbazepine for neuropathic pain Cochrane Reviews, April 2, 2013 Review Article
8 The relationship between serum levels of vitamin D and migraine Journal of Research in Medical Sciences, March 12, 2013 Evidence Based Medicine
9 Cost-effectiveness of apixaban, dabigatran, rivaroxaban, and warfarin for stroke prevention in atrial fibrillation Stroke, May 29, 2013
10 Potential impact of new oral anticoagulants on the management of atrial fibrillation-related stroke in primary care International Journal of Clinical Practice, May 7, 2013
11 Operative mortality and stroke after on-pump vs off-pump surgery in high-risk patients: an analysis of 83 914 coronary bypass operations European Journal of Cardio-Thoracic Surgery, May 20, 2013
12 New Evidence for Therapies in Stroke Rehabilitation Current Atherosclerosis Reports, May 3, 2013 Evidence Based Medicine Review Article
13 The effects of long-term interferon- beta-1b treatment on cognitive functioning in multiple sclerosis: a 16-year longitudinal study Multiple Sclerosis Journal, May 10, 2013
14 Headaches during pregnancy Clinical Obstetrics and Gynecology, May 8, 2013
15 Atrial fibrillation in young stroke patients European Journal of Neurology, May 22, 2013
16 Aspirin with or without an antiemetic for acute migraine headaches in adults Cochrane Reviews, May 10, 2013 Evidence Based Medicine
17 Benefits of combined cholinesterase inhibitor and memantine treatment in moderate-severe Alzheimers disease Alzheimer's & Dementia, May 13, 2013 Review Article
18 Paracetamol (Acetaminophen) in stroke 2 (PAIS 2): Protocol for a randomized, placebo-controlled, double-blind clinical trial to assess the effect of high-dose paracetamol on functional outcome in patients with acute stroke and a body temperature of 36·5°C or above International Journal of Stroke, May 28, 2013
19 Inhaled Sevoflurane May Promote Progression of Amnestic Mild Cognitive Impairment: A Prospective, Randomized Parallel-Group Study The American Journal of the Medical Sciences, April 23, 2013
20 Dietary calcium intake and risk of stroke: a dose-response meta-analysis American Journal of Clinical Nutrition, April 5, 2013 Evidence Based Medicine
Indexed Journals in Neurology: Current Opinion in Neurology, Stroke, Seizure, Cephalgia, Brain Injury more
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