What’s your first-line option for current Neurology information? MDLinx Neurology! Where else but MDLinx Neurology will you find subspecialty coverage of articles published on dementia, headache, movement disorders, neurologic oncology, neurosensory disorders, neurosurgery, pain medicine, pediatric neurology, sleep, spine and more? Also discover the latest clinical pearls from the Smartest Neurologist daily quiz competition and Neurology Physician Review. In less than five minutes a day, you can skim the summaries of pertinent articles within 24 hours of publication. Do you need the 2-minute update? Skip to the highlights from our physician editor, D. Scott Cunningham, MD, PhD, for the “can’t miss” summaries on hot topics in neurology and related subspecialties.
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In a study involving 87,025 postmenopausal women in the Women’s Health Initiative Observational Study, there were 1049 incident cases of ischemic stroke over 663,041 person-years of follow-up. Women in the highest quintile of trans fat intake were at increased risk of ischemic stroke (HR = 1.39) compared with women in the lowest quintile of trans fat intake. Aspirin use modulated the effect of trans fats; ASA users and ASA non-users had HRs for ischemic stroke of 0.95 and 1.66, respectively. Saturated, monounsaturated, and polyunsaturated fat intake were not associated with ischemic stroke.
Read the article summaryAs published in the Journal of Neurological Sciences, increase tea consumption (> 4 cups/d), and diet consisting of hot and spicy foods, and weight gain increase the likelihood of chronicity in patients with episodic migraines. During a 12-month prospective study involving 188 patients with episodic migraines, 17.7% developed chronic, daily migraines. Other risk factors included low education, a high frequency of headaches, headaches of long duration, allodynia, and increased symptomatic treatment of headaches.
Read the article summaryIn a randomized, double-blind, placebo-controlled trial, the calcium channel antagonist, ginsenoside-Rd, has been shown to improve functional outcomes in patients (n=386) with acute ischemic strokes. The patients received a 14-day infusion of ginsenoside-Rd within 72 hours of stroke onset. The National Institutes of Health Stroke Score was improved at 15 days and the modified Rankin score was improved at 90 days (OR = 1.74).
Read the article summary1 Aspirin nonresponders in patients with ischaemic stroke Blood Coagulation & Fibrinolysis, May 14, 2013
2 Effect of addition of clopidogrel to aspirin on stroke incidence: Meta-analysis of randomized trials International Journal of Stroke, May 23, 2013
3 Triple therapy with deferiprone, idebenone and riboflavin in Friedreich's ataxia – open-label trial Acta Neurologica Scandinavica, May 17, 2013
4 Treatment with statins and ischemic stroke severity Neurology, April 25, 2013
5 Effectiveness of antidementia drugs in delaying Alzheimers disease progression Alzheimer's & Dementia, May 2, 2013
6 Targeted use of heparin, heparinoids, or low-molecular-weight heparin to improve outcome after acute ischaemic stroke: an individual patient data meta-analysis of randomised controlled trials The Lancet Neurology, May 17, 2013 Evidence Based Medicine Review Article
7 Oxcarbazepine for neuropathic pain Cochrane Reviews, April 2, 2013 Review Article
8 The relationship between serum levels of vitamin D and migraine Journal of Research in Medical Sciences, March 12, 2013 Evidence Based Medicine
9 Cost-effectiveness of apixaban, dabigatran, rivaroxaban, and warfarin for stroke prevention in atrial fibrillation Stroke, May 29, 2013
10 Potential impact of new oral anticoagulants on the management of atrial fibrillation-related stroke in primary care International Journal of Clinical Practice, May 7, 2013
11 Operative mortality and stroke after on-pump vs off-pump surgery in high-risk patients: an analysis of 83 914 coronary bypass operations European Journal of Cardio-Thoracic Surgery, May 20, 2013
12 New Evidence for Therapies in Stroke Rehabilitation Current Atherosclerosis Reports, May 3, 2013 Evidence Based Medicine Review Article
13 The effects of long-term interferon- beta-1b treatment on cognitive functioning in multiple sclerosis: a 16-year longitudinal study Multiple Sclerosis Journal, May 10, 2013
14 Headaches during pregnancy Clinical Obstetrics and Gynecology, May 8, 2013
15 Atrial fibrillation in young stroke patients European Journal of Neurology, May 22, 2013
16 Aspirin with or without an antiemetic for acute migraine headaches in adults Cochrane Reviews, May 10, 2013 Evidence Based Medicine
17 Benefits of combined cholinesterase inhibitor and memantine treatment in moderate-severe Alzheimers disease Alzheimer's & Dementia, May 13, 2013 Review Article
18 Paracetamol (Acetaminophen) in stroke 2 (PAIS 2): Protocol for a randomized, placebo-controlled, double-blind clinical trial to assess the effect of high-dose paracetamol on functional outcome in patients with acute stroke and a body temperature of 36·5°C or above International Journal of Stroke, May 28, 2013
19 Inhaled Sevoflurane May Promote Progression of Amnestic Mild Cognitive Impairment: A Prospective, Randomized Parallel-Group Study The American Journal of the Medical Sciences, April 23, 2013
20 Dietary calcium intake and risk of stroke: a dose-response meta-analysis American Journal of Clinical Nutrition, April 5, 2013 Evidence Based Medicine
Indexed Journals in Neurology: Current Opinion in Neurology, Stroke, Seizure, Cephalgia, Brain Injury more
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