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Neurology - Neuro/Psych pharmacology News & Articles
What’s your first-line option for current Neurology information? MDLinx Neurology! Where else but MDLinx Neurology will you find subspecialty coverage of articles published on dementia, headache, movement disorders, neurologic oncology, neurosensory disorders, neurosurgery, pain medicine, pediatric neurology, sleep, spine and more? Also discover the latest clinical pearls from the Smartest Neurologist daily quiz competition and Neurology Physician Review. In less than five minutes a day, you can skim the summaries of pertinent articles within 24 hours of publication. Do you need the 2-minute update? Skip to the highlights from our physician editor, D. Scott Cunningham, MD, PhD, for the “can’t miss” summaries on hot topics in neurology and related subspecialties.
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Latest (4) Full Text Articles (245) Focus on Neurodegenerative Diseases41 Switch from selegiline to rasagiline is beneficial in patients with Parkinsons disease Journal of Neural Transmission, May 9, 2013 Clinical Article
42 Intrabodies as Neuroprotective Therapeutics Neurotherapeutics, May 9, 2013 Review Article
43 Clinical spectrum and treatment outcome of West Syndrome in children from Northern India Seizure - European Journal of Epilepsy, May 9, 2013 Clinical Article
44 Drug use in patients with dementia: a register-based study in the health region of Girona (Catalonia/Spain) European Journal of Clinical Pharmacology, May 9, 2013 Clinical Article
45 Deep brain stimulation of the subthalamic nucleus reverses oral tremor in pharmacological models of parkinsonism: interaction with the effects of adenosine A2A antagonism European Journal of Neuroscience, May 9, 2013 Review Article
46 Combined White Matter Imaging Suggests Myelination Defects in Visual Processing Regions in Schizophrenia Neuropsychopharmacology, May 9, 2013 Clinical Article
47 Successful pre-surgical management by intravenous steroid therapy in spinal dural arteriovenous fistula Full Text Neurology and Clinical Neuroscience, May 8, 2013 Clinical Article
48 Potential impact of new oral anticoagulants on the management of atrial fibrillation-related stroke in primary care International Journal of Clinical Practice, May 7, 2013 Clinical Article
49 The case for soluble Aβ oligomers as a drug target in Alzheimers disease Trends in Pharmacological Sciences, May 7, 2013 Review Article
50 Autocrine motility factor injection for motor plate regeneration and muscle function restoration--a pilot study Acta Neurochirurgica, May 7, 2013 Clinical Article
51 Role of Reflexology and Antiepileptic Drugs in Managing Intractable Epilepsy - a Randomized Controlled Trial Research in Complementary Medicine, May 6, 2013 Clinical Article
52 A prospective, randomized, multicentre trial for the treatment of refractory status epilepticus; experiences from evaluating the effect of the novel drug candidate, NS1209 Epilepsy Research, May 6, 2013 Clinical Article
53 Managing depression in patients with advanced heart failure awaiting transplantation American Journal of Health-System Pharmacy, May 6, 2013 Clinical Article
54 The quest for rational antiepileptic polytherapy with supraadditive anticonvulsant efficacy Epilepsy & Behavior, May 6, 2013 Review Article
55 Effectively managing intractable central hyperthermia in a stroke patient by bromocriptine: a case report Full Text Neuropsychiatric Disease and Treatment, May 6, 2013
56 Seizures and antiepileptic drugs in patients with spontaneous intracerebral hemorrhages Seizure - European Journal of Epilepsy, May 3, 2013 Clinical Article
57 Dual-energy X-ray absorptiometry versus quantitative ultrasonography in diagnosing osteoporosis in patients with refractory epilepsy and chronic antiepileptic drug use Therapeutic Advances in Musculoskeletal Disease, May 3, 2013 Clinical Article
58 Degradation of Stored Movement Representations in the Parkinsonian Brain and the Impact of Levodopa Neuropsychologia, May 3, 2013 Clinical Article
59 Brain And Retinal Microglia In Health And Disease: An Unrecognized Target Of The Renin-Angiotensin System Clinical and Experimental Pharmacology and Physiology, May 3, 2013 Clinical Article
60 Long-term effectiveness of acetazolamide on permanent weakness in hyperkalemic periodic paralysis Neuromuscular Disorders, May 3, 2013
Clinical Pearls in Neurology
- Light-to-moderate alcohol consumption may be associated with a reduced risk of incident overall dementia and Alzheimer’s Disease
- 3 months’ topiramate therapy for migraine prophylaxis decreases waist circumference, abdominal skinfold measurements, and body fat ratio
- For individuals with epilepsy, the risk having a broadly defined psychotic disorder is increased by 5.5-fold. The risk of having bipolar disorder is increased by 6.3-fold, and of having schizophrenia increases by 8.5-fold
Highlights in Neurology
Trans fat intake increases risk of ischemic stroke
In a study involving 87,025 postmenopausal women in the Women’s Health Initiative Observational Study, there were 1049 incident cases of ischemic stroke over 663,041 person-years of follow-up. Women in the highest quintile of trans fat intake were at increased risk of ischemic stroke (HR = 1.39) compared with women in the lowest quintile of trans fat intake. Aspirin use modulated the effect of trans fats; ASA users and ASA non-users had HRs for ischemic stroke of 0.95 and 1.66, respectively. Saturated, monounsaturated, and polyunsaturated fat intake were not associated with ischemic stroke.
Read the article summaryNew risk factors for chronic migraine identified
As published in the Journal of Neurological Sciences, increase tea consumption (> 4 cups/d), and diet consisting of hot and spicy foods, and weight gain increase the likelihood of chronicity in patients with episodic migraines. During a 12-month prospective study involving 188 patients with episodic migraines, 17.7% developed chronic, daily migraines. Other risk factors included low education, a high frequency of headaches, headaches of long duration, allodynia, and increased symptomatic treatment of headaches.
Read the article summaryGinsenoside-Rd improves outcomes in patients with acute ischemic stroke
In a randomized, double-blind, placebo-controlled trial, the calcium channel antagonist, ginsenoside-Rd, has been shown to improve functional outcomes in patients (n=386) with acute ischemic strokes. The patients received a 14-day infusion of ginsenoside-Rd within 72 hours of stroke onset. The National Institutes of Health Stroke Score was improved at 15 days and the modified Rankin score was improved at 90 days (OR = 1.74).
Read the article summaryMost Popular Neurology Articles
Last month's top read Top Articles of 20121 Risk of ischemic stroke with the use of risperidone, quetiapine and olanzapine in elderly patients: a population-based, case-crossover study Journal of Psychopharmacology, April 9, 2013
2 Dalfampridine extended release tablets: 1 year of postmarketing safety experience in the US Neuropsychiatric Disease and Treatment, April 1, 2013 Free full text
3 Prophylactic Effects of Duloxetine on Post-Stroke Depression Symptoms: An Open Single-Blind Trial European Neurology, April 2, 2013
4 Levetiracetam in children, adolescents and young adults with intractable epilepsy: Efficacy, tolerability and effect on electroencephalogram - A pilot study European Journal of Paediatric Neurology, April 8, 2013
5 Ischemic Colitis with Type I Interferons Used in the Treatment of Hepatitis C and Multiple Sclerosis: An Evaluation from the Food and Drug Administration Adverse Event Reporting System and Review of the Literature Annals of Pharmacotherapy, April 4, 2013 Review Article
6 Bevacizumab and central nervous system (CNS) hemorrhage Cancer Chemotherapy and Pharmacology, April 10, 2013
7 Novel oral anticoagulants for stroke prevention in atrial fibrillation: a focus on the older patient International Journal of General Medicine, April 11, 2013 Free full text
8 Tiagabine-induced stupor in patients with psychogenic nonepileptic seizures: Nonconvulsive status epilepticus or encephalopathy Epilepsy & Behavior, April 12, 2013
9 Intravenous topiramate: Safety and pharmacokinetics following a single dose in patients with epilepsy or migraines taking oral topiramate Epilepsia, April 22, 2013
10 Risk of Stroke or Systemic Embolism in Atrial Fibrillation Patients Treated With Warfarin Stroke, April 23, 2013
11 Effect of switching hepatic enzyme-inducer antiepileptic drug to levetiracetam on bone mineral density, 25 hydroxyvitamin D, and parathyroid hormone in young adult patients with epilepsy Epilepsia, April 17, 2013
12 Lack of effect of lacosamide on the pharmacokinetic and pharmacodynamic profiles of warfarin Epilepsia, April 26, 2013
13 Effect of eslicarbazepine acetate on the pharmacokinetics of a combined ethinylestradiol/levonorgestrel oral contraceptive in healthy women Epilepsy Research, April 18, 2013
14 Efficacy and safety of dabigatran etexilate and warfarin in real world patients with atrial fibrillation: A prospective nationwide cohort study JACC - Journal of the American College of Cardiology, April 15, 2013
15 Rotigotine and specific non-motor symptoms of Parkinsons disease: Post hoc analysis of RECOVER Parkinsonism & Related Disorders, April 5, 2013
16 Sulthiame add-on therapy for epilepsy Cochrane Reviews, April 5, 2013 Evidence Based Medicine
17 The use of recombinant factor VIIa in warfarin patients with traumatic brain injury: a retrospective case–control study Blood Coagulation & Fibrinolysis, April 5, 2013
18 Association of statin use with risk of dementia: A meta-analysis of prospective cohort studies Geriatrics and Gerontology International, March 8, 2013 Evidence Based Medicine
19 Plasma Exchange for Steroid-Refractory Relapses in Multiple Sclerosis: An Observational, MRI Pilot Study Clinical Therapeutics, April 29, 2013
20 Central functional response to the novel peptide cannabinoid, hemopressin Neuropharmacology, April 29, 2013
Indexed Journals in Neurology: Current Opinion in Neurology, Stroke, Seizure, Cephalgia, Brain Injury more
Other Topics in Neurology
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