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Neurology - Demyelinating Disorders News & Articles
What’s your first-line option for current Neurology information? MDLinx Neurology! Where else but MDLinx Neurology will you find subspecialty coverage of articles published on dementia, headache, movement disorders, neurologic oncology, neurosensory disorders, neurosurgery, pain medicine, pediatric neurology, sleep, spine and more? Also discover the latest clinical pearls from the Smartest Neurologist daily quiz competition and Neurology Physician Review. In less than five minutes a day, you can skim the summaries of pertinent articles within 24 hours of publication. Do you need the 2-minute update? Skip to the highlights from our physician editor, D. Scott Cunningham, MD, PhD, for the “can’t miss” summaries on hot topics in neurology and related subspecialties.
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Articles
Latest (5) Full Text Articles (94) Focus on Neurological Infections41 Predicting multiple sclerosis following isolated optic neuritis in children European Journal of Neurology, May 14, 2013 Clinical Article
42 Management of Secondary Progressive Multiple Sclerosis: Prophylactic Treatment--Past, Present, and Future Aspects Current Treatment Options in Neurology, May 13, 2013 Clinical Article
43 The effects of long-term interferon- beta-1b treatment on cognitive functioning in multiple sclerosis: a 16-year longitudinal study Multiple Sclerosis Journal, May 10, 2013 Clinical Article
44 A Feasibility Study to Investigate the Effect of Functional Electrical Stimulation and Physiotherapy Exercise on the Quality of Gait of People With Multiple Sclerosis Neuromodulation: Technology at the Neural Interface, May 10, 2013 Clinical Article
45 The economic impact of multiple sclerosis in Australia in 2010 Multiple Sclerosis Journal, May 10, 2013 Clinical Article
46 Cost-effectiveness of injectable disease-modifying therapies for the treatment of relapsing forms of multiple sclerosis in Spain The European Journal of Health Economics, May 10, 2013 Clinical Article
47 Disease course and outcome of 15 monocentrically treated natalizumab-associated progressive multifocal leukoencephalopathy patients Journal of Neurology, Neurosurgery & Psychiatry, May 9, 2013 Clinical Article
48 Developmental maturation of innate immune cell function correlates with susceptibility to central nervous system autoimmunity European Journal of Immunology, May 9, 2013 Clinical Article
49 Lipid profiles are associated with lesion formation over 24 months in interferon-{beta} treated patients following the first demyelinating event Journal of Neurology, Neurosurgery & Psychiatry, May 9, 2013 Clinical Article
50 IFN-β therapy modulates B-cell and monocyte crosstalk via TLR7 in multiple sclerosis patients European Journal of Immunology, May 9, 2013 Clinical Article
51 Value of the MoCA Test as a Screening Instrument in Multiple Sclerosis The Canadian Journal of Neurological Sciences, May 9, 2013 Clinical Article
52 Serum and cerebrospinal fluid heavy neurofilaments and antibodies against them in early multiple sclerosis Journal of Neuroimmunology, May 8, 2013 Clinical Article
53 Anti-JC virus antibody prevalence in a multinational multiple sclerosis cohort Multiple Sclerosis Journal, May 8, 2013 Clinical Article
54 Treatment Optimization in MS: Canadian MS Working Group Updated Recommendations The Canadian Journal of Neurological Sciences, May 8, 2013 Review Article
55 Increased thyroid autoimmunity among women with multiple sclerosis in the postpartum setting Multiple Sclerosis Journal, May 7, 2013 Review Article
56 Comparative Effectiveness of Early Natalizumab Treatment in JC Virus'Negative Relapsing-Remitting Multiple Sclerosis Full Text The American Journal of Managed Care, May 6, 2013 Review Article
57 Do generic utility measures capture what is important to the quality of life of people with multiple sclerosis Full Text Health and Quality of Life Outcomes , May 6, 2013 Review Article
58 An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study The Lancet Neurology, May 6, 2013 Review Article
59 What is the relevance of quality of life assessment for patients with attention impairment Full Text Health and Quality of Life Outcomes , May 6, 2013 Review Article
60 The reliability, precision and clinically meaningful change of walking assessments in multiple sclerosis Multiple Sclerosis Journal, May 6, 2013 Review Article
Clinical Pearls in Neurology
- Light-to-moderate alcohol consumption may be associated with a reduced risk of incident overall dementia and Alzheimer’s Disease
- 3 months’ topiramate therapy for migraine prophylaxis decreases waist circumference, abdominal skinfold measurements, and body fat ratio
- For individuals with epilepsy, the risk having a broadly defined psychotic disorder is increased by 5.5-fold. The risk of having bipolar disorder is increased by 6.3-fold, and of having schizophrenia increases by 8.5-fold
Highlights in Neurology
Trans fat intake increases risk of ischemic stroke
In a study involving 87,025 postmenopausal women in the Women’s Health Initiative Observational Study, there were 1049 incident cases of ischemic stroke over 663,041 person-years of follow-up. Women in the highest quintile of trans fat intake were at increased risk of ischemic stroke (HR = 1.39) compared with women in the lowest quintile of trans fat intake. Aspirin use modulated the effect of trans fats; ASA users and ASA non-users had HRs for ischemic stroke of 0.95 and 1.66, respectively. Saturated, monounsaturated, and polyunsaturated fat intake were not associated with ischemic stroke.
Read the article summaryNew risk factors for chronic migraine identified
As published in the Journal of Neurological Sciences, increase tea consumption (> 4 cups/d), and diet consisting of hot and spicy foods, and weight gain increase the likelihood of chronicity in patients with episodic migraines. During a 12-month prospective study involving 188 patients with episodic migraines, 17.7% developed chronic, daily migraines. Other risk factors included low education, a high frequency of headaches, headaches of long duration, allodynia, and increased symptomatic treatment of headaches.
Read the article summaryGinsenoside-Rd improves outcomes in patients with acute ischemic stroke
In a randomized, double-blind, placebo-controlled trial, the calcium channel antagonist, ginsenoside-Rd, has been shown to improve functional outcomes in patients (n=386) with acute ischemic strokes. The patients received a 14-day infusion of ginsenoside-Rd within 72 hours of stroke onset. The National Institutes of Health Stroke Score was improved at 15 days and the modified Rankin score was improved at 90 days (OR = 1.74).
Read the article summaryMost Popular Neurology Articles
Last month's top read Top Articles of 20121 Cerebrospinal fluid oligoclonal bands in multiple sclerosis and clinically isolated syndromes: a meta-analysis of prevalence, prognosis and effect of latitude Journal of Neurology, Neurosurgery & Psychiatry, March 26, 2013
2 Targeting B cells in the treatment of multiple sclerosis: recent advances and remaining challenges Therapeutic Advances in Neurological Disorders, April 15, 2013
3 Daclizumab high-yield process in relapsing-remitting multiple sclerosis (SELECT): a randomised, double-blind, placebo-controlled trial The Lancet, April 5, 2013
4 Modulation of dendritic cell properties by laquinimod as a mechanism for modulating multiple sclerosis Brain, April 11, 2013
5 Sexual Disparities in the Incidence and Course of MS Clinical Immunology, April 9, 2013 Review Article
6 Clinical and biomarker assessment of demyelinating events suggesting multiple sclerosis Acta Neurologica Scandinavica, April 22, 2013
7 Role of oral teriflunomide in the management of multiple sclerosis Neuropsychiatric Disease and Treatment, April 23, 2013 Free full text
8 A systematic review of randomized, double-blind, placebo-controlled trials examining the clinical efficacy of Vitamin D in multiple sclerosis Neuroepidemiology , March 20, 2013
9 Epstein-Barr virus antibodies and vitamin D in prospective multiple sclerosis biobank samples Multiple Sclerosis Journal, April 4, 2013
10 Dalfampridine extended release tablets: 1 year of postmarketing safety experience in the US Neuropsychiatric Disease and Treatment, April 1, 2013 Free full text
11 Incidence and Prevalence of Multiple Sclerosis in the Americas: A Systematic Review Neuroepidemiology , March 27, 2013
12 Role of puberty in multiple sclerosis risk and course Clinical Immunology, April 17, 2013 Review Article
13 Plasma Exchange for Steroid-Refractory Relapses in Multiple Sclerosis: An Observational, MRI Pilot Study Clinical Therapeutics, April 29, 2013
14 Safinamide and flecainide protect axons and reduce microglial activation in models of multiple sclerosis Brain, April 11, 2013 Review Article
15 Optimisation of MRI for the detection of small veins in multiple sclerosis at 3T and 7T European Journal of Radiology, April 3, 2013
16 Anti-JC virus antibody prevalence in a multinational multiple sclerosis cohort Multiple Sclerosis Journal, April 1, 2013
17 Occupational Exposure and Risk of Central Nervous System Demyelination American Journal of Epidemiology, April 16, 2013
18 Group exercise training for balance, functional status, spasticity, fatigue and quality of life in multiple sclerosis: a randomized controlled trial Clinical Rehabilitation, April 19, 2013
19 Multiple Sclerosis: Validation of MR Imaging for Quantification and Detection of Iron Radiology, April 24, 2013
20 Oral versus intravenous steroids for treatment of relapses in multiple sclerosis Cochrane Reviews, January 10, 2013
Indexed Journals in Neurology: Current Opinion in Neurology, Stroke, Seizure, Cephalgia, Brain Injury more
Other Topics in Neurology
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