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Neurology - Demyelinating Disorders News & Articles
What’s your first-line option for current Neurology information? MDLinx Neurology! Where else but MDLinx Neurology will you find subspecialty coverage of articles published on dementia, headache, movement disorders, neurologic oncology, neurosensory disorders, neurosurgery, pain medicine, pediatric neurology, sleep, spine and more? Also discover the latest clinical pearls from the Smartest Neurologist daily quiz competition and Neurology Physician Review. In less than five minutes a day, you can skim the summaries of pertinent articles within 24 hours of publication. Do you need the 2-minute update? Skip to the highlights from our physician editor, D. Scott Cunningham, MD, PhD, for the “can’t miss” summaries on hot topics in neurology and related subspecialties.
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Articles
Latest (8) Full Text Articles (94) Focus on Dementia401 Effective management of lower urinary tract dysfunction in idiopathic Parkinsons disease International Journal of Urology, November 16, 2012
402 Impact of electroacupuncture on quality of life for patients with Relapsing-Remitting Multiple Sclerosis under treatment with immunomodulators: A randomized study Full Text BMC Complementary and Alternative Medicine, November 15, 2012 Clinical Article
403 Comparison of Quality of Life Between Two Clinical Conditions With Immunosuppressive Therapy: Liver Transplantation and Multiple Sclerosis Transplantation Proceedings, November 15, 2012 Clinical Article
404 Risk of fractures in patients with multiple sclerosis: record-linkage study Full Text BMC Neurology, November 15, 2012
405 Exercise in the community for people with multiple sclerosis — a follow-up of people with minimal gait impairment Multiple Sclerosis Journal, November 14, 2012 Clinical Article
406 Concurrence of multiple sclerosis and amyotrophic lateral sclerosis in patients with hexanucleotide repeat expansions of C9ORF72 Journal of Neurology, Neurosurgery & Psychiatry, November 14, 2012
407 Validity and variability of the 5-repetition sit-to-stand test in patients with multiple sclerosis Disability & Rehabilitation, November 13, 2012 Clinical Article
408 Adherence to MRI protocol consensus guidelines in multiple sclerosis: An Australian multi-centre study Journal of Medical Imaging and Radiation Oncology, November 13, 2012
409 Polyarteritis nodosa with central nervous system involvement mimicking relapsing-remitting multiple sclerosis Modern Rheumatology, November 13, 2012
410 Co-occurrence of two cases of progressive multifocal leukoencephalopathy in a natalizumab “infusion group” Multiple Sclerosis Journal, November 12, 2012
411 Acute disseminated encephalomyelitis followed by recurrent or monophasic optic neuritis in pediatric patients Multiple Sclerosis Journal, November 12, 2012 Clinical Article
412 Exercise in the community for people with minimal gait impairment due to MS: an assessor-blind randomized controlled trial Multiple Sclerosis Journal, November 9, 2012 Clinical Article
413 Preliminary study on the association of AQP4 promoter polymorphism with anti-aquaporin-4 antibody positivity in Southern Han Chinese patients with idiopathic demyelinating disorders of central nervous system Journal of Neuroimmunology, November 9, 2012
414 Time to secondary progression in patients with multiple sclerosis who were treated with first generation immunomodulating drugs Multiple Sclerosis Journal, November 8, 2012 Clinical Article
415 Phosphorylated neurofilament heavy subunit (pNF-H) in peripheral blood and CSF as a potential prognostic biomarker in amyotrophic lateral sclerosis Journal of Neurology, Neurosurgery & Psychiatry, November 7, 2012 Clinical Article
416 A systematic review of research undertaken in vocational rehabilitation for people with multiple sclerosis Disability & Rehabilitation, November 6, 2012 Clinical Article
417 Suicide risk in multiple sclerosis: A systematic review of current literature Journal of Psychosomatic Research, November 6, 2012
418 Voxel-wise mapping of cervical cord damage in multiple sclerosis patients with different clinical phenotypes Journal of Neurology, Neurosurgery & Psychiatry, November 5, 2012 Clinical Article
419 A Randomized Phase I Study of Methanesulfonyl Fluoride, an Irreversible Cholinesterase Inhibitor, for the Treatment of Alzheimer's Disease British Journal of Clinical Pharmacology, November 5, 2012
420 Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: a randomised controlled phase 3 trial The Lancet - Early Online Publication, November 2, 2012 Clinical Article
Clinical Pearls in Neurology
- Light-to-moderate alcohol consumption may be associated with a reduced risk of incident overall dementia and Alzheimer’s Disease
- 3 months’ topiramate therapy for migraine prophylaxis decreases waist circumference, abdominal skinfold measurements, and body fat ratio
- For individuals with epilepsy, the risk having a broadly defined psychotic disorder is increased by 5.5-fold. The risk of having bipolar disorder is increased by 6.3-fold, and of having schizophrenia increases by 8.5-fold
Highlights in Neurology
Trans fat intake increases risk of ischemic stroke
In a study involving 87,025 postmenopausal women in the Women’s Health Initiative Observational Study, there were 1049 incident cases of ischemic stroke over 663,041 person-years of follow-up. Women in the highest quintile of trans fat intake were at increased risk of ischemic stroke (HR = 1.39) compared with women in the lowest quintile of trans fat intake. Aspirin use modulated the effect of trans fats; ASA users and ASA non-users had HRs for ischemic stroke of 0.95 and 1.66, respectively. Saturated, monounsaturated, and polyunsaturated fat intake were not associated with ischemic stroke.
Read the article summaryNew risk factors for chronic migraine identified
As published in the Journal of Neurological Sciences, increase tea consumption (> 4 cups/d), and diet consisting of hot and spicy foods, and weight gain increase the likelihood of chronicity in patients with episodic migraines. During a 12-month prospective study involving 188 patients with episodic migraines, 17.7% developed chronic, daily migraines. Other risk factors included low education, a high frequency of headaches, headaches of long duration, allodynia, and increased symptomatic treatment of headaches.
Read the article summaryGinsenoside-Rd improves outcomes in patients with acute ischemic stroke
In a randomized, double-blind, placebo-controlled trial, the calcium channel antagonist, ginsenoside-Rd, has been shown to improve functional outcomes in patients (n=386) with acute ischemic strokes. The patients received a 14-day infusion of ginsenoside-Rd within 72 hours of stroke onset. The National Institutes of Health Stroke Score was improved at 15 days and the modified Rankin score was improved at 90 days (OR = 1.74).
Read the article summaryMost Popular Neurology Articles
Last month's top read Top Articles of 20121 Cerebrospinal fluid oligoclonal bands in multiple sclerosis and clinically isolated syndromes: a meta-analysis of prevalence, prognosis and effect of latitude Journal of Neurology, Neurosurgery & Psychiatry, March 26, 2013
2 Targeting B cells in the treatment of multiple sclerosis: recent advances and remaining challenges Therapeutic Advances in Neurological Disorders, April 15, 2013
3 Daclizumab high-yield process in relapsing-remitting multiple sclerosis (SELECT): a randomised, double-blind, placebo-controlled trial The Lancet, April 5, 2013
4 Modulation of dendritic cell properties by laquinimod as a mechanism for modulating multiple sclerosis Brain, April 11, 2013
5 Sexual Disparities in the Incidence and Course of MS Clinical Immunology, April 9, 2013 Review Article
6 Clinical and biomarker assessment of demyelinating events suggesting multiple sclerosis Acta Neurologica Scandinavica, April 22, 2013
7 Role of oral teriflunomide in the management of multiple sclerosis Neuropsychiatric Disease and Treatment, April 23, 2013 Free full text
8 A systematic review of randomized, double-blind, placebo-controlled trials examining the clinical efficacy of Vitamin D in multiple sclerosis Neuroepidemiology , March 20, 2013
9 Epstein-Barr virus antibodies and vitamin D in prospective multiple sclerosis biobank samples Multiple Sclerosis Journal, April 4, 2013
10 Dalfampridine extended release tablets: 1 year of postmarketing safety experience in the US Neuropsychiatric Disease and Treatment, April 1, 2013 Free full text
11 Incidence and Prevalence of Multiple Sclerosis in the Americas: A Systematic Review Neuroepidemiology , March 27, 2013
12 Role of puberty in multiple sclerosis risk and course Clinical Immunology, April 17, 2013 Review Article
13 Plasma Exchange for Steroid-Refractory Relapses in Multiple Sclerosis: An Observational, MRI Pilot Study Clinical Therapeutics, April 29, 2013
14 Safinamide and flecainide protect axons and reduce microglial activation in models of multiple sclerosis Brain, April 11, 2013 Review Article
15 Optimisation of MRI for the detection of small veins in multiple sclerosis at 3T and 7T European Journal of Radiology, April 3, 2013
16 Anti-JC virus antibody prevalence in a multinational multiple sclerosis cohort Multiple Sclerosis Journal, April 1, 2013
17 Occupational Exposure and Risk of Central Nervous System Demyelination American Journal of Epidemiology, April 16, 2013
18 Group exercise training for balance, functional status, spasticity, fatigue and quality of life in multiple sclerosis: a randomized controlled trial Clinical Rehabilitation, April 19, 2013
19 Multiple Sclerosis: Validation of MR Imaging for Quantification and Detection of Iron Radiology, April 24, 2013
20 Oral versus intravenous steroids for treatment of relapses in multiple sclerosis Cochrane Reviews, January 10, 2013
Indexed Journals in Neurology: Current Opinion in Neurology, Stroke, Seizure, Cephalgia, Brain Injury more
Other Topics in Neurology
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