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Neurology - Demyelinating Disorders News & Articles
What’s your first-line option for current Neurology information? MDLinx Neurology! Where else but MDLinx Neurology will you find subspecialty coverage of articles published on dementia, headache, movement disorders, neurologic oncology, neurosensory disorders, neurosurgery, pain medicine, pediatric neurology, sleep, spine and more? Also discover the latest clinical pearls from the Smartest Neurologist daily quiz competition and Neurology Physician Review. In less than five minutes a day, you can skim the summaries of pertinent articles within 24 hours of publication. Do you need the 2-minute update? Skip to the highlights from our physician editor, D. Scott Cunningham, MD, PhD, for the “can’t miss” summaries on hot topics in neurology and related subspecialties.
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Articles
Latest (5) Full Text Articles (94) Focus on Inflammatory Diseases201 Cognitive Processing Speed is Related to Fall Frequency in Older Adults with Multiple Sclerosis Archives of Physical Medicine and Rehabilitation, March 12, 2013 Clinical Article
202 Steps Per Day Among Persons With Multiple Sclerosis: Variation by Demographic, Clinical, and Device Characteristics Archives of Physical Medicine and Rehabilitation, March 12, 2013 Clinical Article
203 Leukocyte counts in cerebrospinal fluid and blood following firategrast treatment in subjects with relapsing forms of multiple sclerosis European Journal of Neurology, March 11, 2013 Clinical Article
204 Alemtuzumab: evidence for its potential in relapsing-remitting multiple sclerosis Full Text Drug Design, Development and Therapy, March 11, 2013 Clinical Article
205 Cerebral white matter blood flow and energy metabolism in multiple sclerosis Multiple Sclerosis Journal, March 11, 2013 Clinical Article
206 Seizure characteristics in multiple sclerosis patients Journal of Research in Medical Sciences, March 11, 2013 Clinical Article
207 Artificial reproductive techniques in Multiple Sclerosis Clinical Immunology, March 11, 2013 Review Article
208 A second-generation ELISA (STRATIFY JCV DxSelect) for detection of JC virus antibodies in human serum and plasma to support progressive multifocal leukoencephalopathy risk stratification Journal of Clinical Virology, March 11, 2013 Clinical Article
209 Sensory chronic inflammatory demyelinating polyneuropathy: An under-recognized entity Muscle & Nerve, March 11, 2013 Review Article
210 Amelioration of autoimmune neuroinflammation by the fusion molecule Fn14.TRAIL Full Text Journal of Neuroinflammation, March 11, 2013 Review Article
211 RNA dysfunction and aggrephagy at the centre of an amyotrophic lateral sclerosis/frontotemporal dementia disease continuum Brain, March 11, 2013 Review Article
212 Orofacial Apraxia in Motor Neuron Disease Full Text Case Reports in Neurology, March 8, 2013
213 Loss of TDP-43 causes age-dependent progressive motor neuron degeneration Brain, March 7, 2013 Review Article
214 Natalizumab Therapy for Highly Active Pediatric Multiple Sclerosis Natalizumab Therapy for Highly Active Pediatric MS JAMA Neurology, March 6, 2013 Clinical Article
215 Amantadine and the place of acupuncture in the treatment of fatigue in patients with multiple sclerosis: an observational study Acupuncture in Medicine, March 6, 2013 Clinical Article
216 High and dysregulated secretion of epidermal growth factor from immune cells of patients with relapsing-remitting multiple sclerosis Journal of Neuroimmunology, March 6, 2013 Review Article
217 Acute disseminated encephalomyelitis in two renal transplant patients: is there a role for Epstein-Barr virus reactivation Multiple Sclerosis Journal, March 6, 2013
218 Epidural blood patch in a patient with multiple sclerosis: is it safe? Canadian Journal of Anesthesia, March 6, 2013
219 Magnetic resonance imaging outcomes from a phase III trial of teriflunomide Multiple Sclerosis Journal, March 5, 2013 Clinical Article
220 Regional Cervical Cord Atrophy and Disability in Multiple Sclerosis: A Voxel-based Analysis Radiology, March 5, 2013 Clinical Article
Clinical Pearls in Neurology
- Light-to-moderate alcohol consumption may be associated with a reduced risk of incident overall dementia and Alzheimer’s Disease
- 3 months’ topiramate therapy for migraine prophylaxis decreases waist circumference, abdominal skinfold measurements, and body fat ratio
- For individuals with epilepsy, the risk having a broadly defined psychotic disorder is increased by 5.5-fold. The risk of having bipolar disorder is increased by 6.3-fold, and of having schizophrenia increases by 8.5-fold
Highlights in Neurology
Trans fat intake increases risk of ischemic stroke
In a study involving 87,025 postmenopausal women in the Women’s Health Initiative Observational Study, there were 1049 incident cases of ischemic stroke over 663,041 person-years of follow-up. Women in the highest quintile of trans fat intake were at increased risk of ischemic stroke (HR = 1.39) compared with women in the lowest quintile of trans fat intake. Aspirin use modulated the effect of trans fats; ASA users and ASA non-users had HRs for ischemic stroke of 0.95 and 1.66, respectively. Saturated, monounsaturated, and polyunsaturated fat intake were not associated with ischemic stroke.
Read the article summaryNew risk factors for chronic migraine identified
As published in the Journal of Neurological Sciences, increase tea consumption (> 4 cups/d), and diet consisting of hot and spicy foods, and weight gain increase the likelihood of chronicity in patients with episodic migraines. During a 12-month prospective study involving 188 patients with episodic migraines, 17.7% developed chronic, daily migraines. Other risk factors included low education, a high frequency of headaches, headaches of long duration, allodynia, and increased symptomatic treatment of headaches.
Read the article summaryGinsenoside-Rd improves outcomes in patients with acute ischemic stroke
In a randomized, double-blind, placebo-controlled trial, the calcium channel antagonist, ginsenoside-Rd, has been shown to improve functional outcomes in patients (n=386) with acute ischemic strokes. The patients received a 14-day infusion of ginsenoside-Rd within 72 hours of stroke onset. The National Institutes of Health Stroke Score was improved at 15 days and the modified Rankin score was improved at 90 days (OR = 1.74).
Read the article summaryMost Popular Neurology Articles
Last month's top read Top Articles of 20121 Cerebrospinal fluid oligoclonal bands in multiple sclerosis and clinically isolated syndromes: a meta-analysis of prevalence, prognosis and effect of latitude Journal of Neurology, Neurosurgery & Psychiatry, March 26, 2013
2 Targeting B cells in the treatment of multiple sclerosis: recent advances and remaining challenges Therapeutic Advances in Neurological Disorders, April 15, 2013
3 Daclizumab high-yield process in relapsing-remitting multiple sclerosis (SELECT): a randomised, double-blind, placebo-controlled trial The Lancet, April 5, 2013
4 Modulation of dendritic cell properties by laquinimod as a mechanism for modulating multiple sclerosis Brain, April 11, 2013
5 Sexual Disparities in the Incidence and Course of MS Clinical Immunology, April 9, 2013 Review Article
6 Clinical and biomarker assessment of demyelinating events suggesting multiple sclerosis Acta Neurologica Scandinavica, April 22, 2013
7 Role of oral teriflunomide in the management of multiple sclerosis Neuropsychiatric Disease and Treatment, April 23, 2013 Free full text
8 A systematic review of randomized, double-blind, placebo-controlled trials examining the clinical efficacy of Vitamin D in multiple sclerosis Neuroepidemiology , March 20, 2013
9 Epstein-Barr virus antibodies and vitamin D in prospective multiple sclerosis biobank samples Multiple Sclerosis Journal, April 4, 2013
10 Dalfampridine extended release tablets: 1 year of postmarketing safety experience in the US Neuropsychiatric Disease and Treatment, April 1, 2013 Free full text
11 Incidence and Prevalence of Multiple Sclerosis in the Americas: A Systematic Review Neuroepidemiology , March 27, 2013
12 Role of puberty in multiple sclerosis risk and course Clinical Immunology, April 17, 2013 Review Article
13 Plasma Exchange for Steroid-Refractory Relapses in Multiple Sclerosis: An Observational, MRI Pilot Study Clinical Therapeutics, April 29, 2013
14 Safinamide and flecainide protect axons and reduce microglial activation in models of multiple sclerosis Brain, April 11, 2013 Review Article
15 Optimisation of MRI for the detection of small veins in multiple sclerosis at 3T and 7T European Journal of Radiology, April 3, 2013
16 Anti-JC virus antibody prevalence in a multinational multiple sclerosis cohort Multiple Sclerosis Journal, April 1, 2013
17 Occupational Exposure and Risk of Central Nervous System Demyelination American Journal of Epidemiology, April 16, 2013
18 Group exercise training for balance, functional status, spasticity, fatigue and quality of life in multiple sclerosis: a randomized controlled trial Clinical Rehabilitation, April 19, 2013
19 Multiple Sclerosis: Validation of MR Imaging for Quantification and Detection of Iron Radiology, April 24, 2013
20 Oral versus intravenous steroids for treatment of relapses in multiple sclerosis Cochrane Reviews, January 10, 2013
Indexed Journals in Neurology: Current Opinion in Neurology, Stroke, Seizure, Cephalgia, Brain Injury more
Other Topics in Neurology
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