Neurology - Basic Science/Genetics News & Articles

What’s your first-line option for current Neurology information? MDLinx Neurology! Where else but MDLinx Neurology will you find subspecialty coverage of articles published on dementia, headache, movement disorders, neurologic oncology, neurosensory disorders, neurosurgery, pain medicine, pediatric neurology, sleep, spine and more? Also discover the latest clinical pearls from the Smartest Neurologist daily quiz competition and Neurology Physician Review. In less than five minutes a day, you can skim the summaries of pertinent articles within 24 hours of publication. Do you need the 2-minute update? Skip to the highlights from our physician editor, D. Scott Cunningham, MD, PhD, for the “can’t miss” summaries on hot topics in neurology and related subspecialties.

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Latest (3) Full Text Articles (450) Focus on Headache

Ranked, sorted, and summarized by MDLinx editors from the latest literature

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121 Mitochondrial JNK phosphorylation as a novel therapeutic target to inhibit neuroinflammation and apoptosis after neonatal ischemic brain damage Neurobiology of Disease , April 19, 2013 Review Article

122 Reactive Glia in the Injured Brain Acquire Stem Cell Properties in Response to Sonic Hedgehog Glia Cell Stem Cell, April 18, 2013 Review Article

123 Zinc deficiency regulates hippocampal gene expression and impairs neuronal differentiation Nutritional Neuroscience, April 18, 2013 Review Article

124 Distinct Neural Markers of TVA-Based Visual Processing Speed and Short-Term Storage Capacity Parameters Cerebral Cortex, April 18, 2013 Review Article

125 Effects of Number Magnitude and Notation at 7T: Separating the Neural Response to Small and Large, Symbolic and Nonsymbolic Number Cerebral Cortex, April 18, 2013 Review Article

126 Mutations in the COPII Vesicle Component Gene SEC24B are Associated with Human Neural Tube Defects Human Mutation, April 18, 2013 Review Article

127 Challenging Behavior in Smith-Lemli-Opitz Syndrome: Initial Test of Biobehavioral Influences Cognitive and Behavioral Neurology, April 18, 2013 Review Article

128 β-synuclein aggregates and induces neurodegeneration in dopaminergic neurons Annals of Neurology , April 17, 2013 Review Article

129 Safety/feasibility of targeting the substantia nigra with AAV2-neurturin in Parkinson patients Neurology, April 17, 2013 Review Article

130 Glucocerebrosidase Mutations Tipping Point Toward Parkinson Disease and Dementia JAMA Neurology, April 17, 2013 Review Article

131 C9orf72 Hexanucleotide Repeat Expansion and Guam Amyotrophic Lateral Sclerosis–Parkinsonism-Dementia Complex JAMA Neurology, April 17, 2013 Review Article

132 Proactive control of sequential saccades in the human supplementary eye field Proceedings of the National Academy of Sciences of the United States of America, April 17, 2013 Review Article

133 Intellectual disability and hemizygous GPD2 mutation American Journal of Medical Genetics Part A, April 17, 2013 Review Article

134 Persistent hypertension despite successful dilation of a stenotic renal artery in a boy with neurofibromatosis type 1 American Journal of Medical Genetics Part A, April 17, 2013

135 Prevention and treatment of neurovascular in-stent stenoses: review of the concepts Expert Review of Cardiovascular Therapy , April 16, 2013 Review Article

136 Genome-wide associations of signaling pathways in glioblastoma multiforme Full Text BMC Genomics, April 16, 2013

137 Brain amyloid-β oligomers in ageing and Alzheimers disease Brain, April 16, 2013 Review Article

138 EE-drospirenone-levomefolate calcium versus EE-drospirenone + folic acid: folate status during 24 weeks of treatment and over 20 weeks following treatment cessation Full Text International Journal of Women's Health, April 15, 2013 Clinical Article

139 Myotonic dystrophy type 1 and de novo FSHD mutation double trouble: A clinical and muscle MRI study Neuromuscular Disorders, April 15, 2013

140 A novel mutation expands the genetic and clinical spectrum of MYH7-related myopathies Neuromuscular Disorders, April 15, 2013 Review Article

50 available pages First Previous 7 8 9 10 11 12 13 14 15 16 Next Last

Clinical Pearls in Neurology

Light-to-moderate alcohol consumption may be associated with a reduced risk of incident overall dementia and Alzheimer’s Disease
3 months’ topiramate therapy for migraine prophylaxis decreases waist circumference, abdominal skinfold measurements, and body fat ratio
For individuals with epilepsy, the risk having a broadly defined psychotic disorder is increased by 5.5-fold. The risk of having bipolar disorder is increased by 6.3-fold, and of having schizophrenia increases by 8.5-fold

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Highlights in Neurology

Trans fat intake increases risk of ischemic stroke

In a study involving 87,025 postmenopausal women in the Women’s Health Initiative Observational Study, there were 1049 incident cases of ischemic stroke over 663,041 person-years of follow-up. Women in the highest quintile of trans fat intake were at increased risk of ischemic stroke (HR = 1.39) compared with women in the lowest quintile of trans fat intake. Aspirin use modulated the effect of trans fats; ASA users and ASA non-users had HRs for ischemic stroke of 0.95 and 1.66, respectively. Saturated, monounsaturated, and polyunsaturated fat intake were not associated with ischemic stroke.

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New risk factors for chronic migraine identified

As published in the Journal of Neurological Sciences, increase tea consumption (> 4 cups/d), and diet consisting of hot and spicy foods, and weight gain increase the likelihood of chronicity in patients with episodic migraines. During a 12-month prospective study involving 188 patients with episodic migraines, 17.7% developed chronic, daily migraines. Other risk factors included low education, a high frequency of headaches, headaches of long duration, allodynia, and increased symptomatic treatment of headaches.

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Ginsenoside-Rd improves outcomes in patients with acute ischemic stroke

In a randomized, double-blind, placebo-controlled trial, the calcium channel antagonist, ginsenoside-Rd, has been shown to improve functional outcomes in patients (n=386) with acute ischemic strokes. The patients received a 14-day infusion of ginsenoside-Rd within 72 hours of stroke onset. The National Institutes of Health Stroke Score was improved at 15 days and the modified Rankin score was improved at 90 days (OR = 1.74).

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Most Popular Neurology Articles

Last month's top read Top Articles of 2012

1 Differential Tangential Expansion as a Mechanism for Cortical Gyrification Cerebral Cortex, April 19, 2013 Review Article

2 Mitochondrial Disease in Childhood: Nuclear Encoded Neurotherapeutics, April 3, 2013 Review Article

3 Pregnancy outcomes following gabapentin use: Results of a prospective comparative cohort study Neurology, April 5, 2013

4 Sympathetic regulation of cerebral blood flow in humans: a review British Journal of Anesthesia, April 26, 2013 Review Article

5 Neuronal Morphology Goes Digital: A Research Hub for Cellular and System Neuroscience Neuron, April 9, 2013 Review Article

6 β-synuclein aggregates and induces neurodegeneration in dopaminergic neurons Annals of Neurology , April 17, 2013 Review Article

7 Prevention and treatment of neurovascular in-stent stenoses: review of the concepts Expert Review of Cardiovascular Therapy , April 16, 2013 Review Article

8 British Menopause Society 22nd Annual Conference, Winchester 2012:Menopause and the brain Menopause International, April 11, 2013

9 Impaired pitch perception and memory in congenital amusia: the deficit starts in the auditory cortex Brain, April 26, 2013 Review Article

10 Pregnancy outcome in women exposed to antiepileptic drugs: teratogenic role of maternal epilepsy and its pharmacologic treatment Reproductive Toxicology, April 22, 2013

11 Genome-wide associations of signaling pathways in glioblastoma multiforme BMC Genomics, April 16, 2013 Free full text

12 Parental depression, maternal antidepressant use during pregnancy, and risk of autism spectrum disorders: population based case-control study British Medical Journal, April 23, 2013 Free full text

13 Altered intrinsic brain activity in patients with paroxysmal kinesigenic dyskinesia by PRRT2 mutation Neurological Sciences, April 1, 2013 Review Article

14 Calcium antagonists as an add-on therapy for drug-resistant epilepsy Cochrane Reviews, April 2, 2013 Review Article

15 Non-pharmacological interventions for preventing secondary vascular events after stroke or transient ischemic attack Cochrane Reviews, April 2, 2013 Review Article

16 Aspirin: a review of its neurobiological properties and therapeutic potential for mental illness BMC Medicine, March 19, 2013 Free full text Review Article
Exclusive Author Commentary

17 Glucocerebrosidase Mutations Tipping Point Toward Parkinson Disease and Dementia JAMA Neurology, April 17, 2013 Review Article

18 Reactive Glia in the Injured Brain Acquire Stem Cell Properties in Response to Sonic Hedgehog Glia Cell Stem Cell, April 18, 2013 Review Article

19 Safety/feasibility of targeting the substantia nigra with AAV2-neurturin in Parkinson patients Neurology, April 17, 2013 Review Article

20 Prion infectivity in the spleen of a PRNP heterozygous individual with subclinical variant Creutzfeldt-Jakob disease Brain, April 23, 2013 Review Article

Indexed Journals in Neurology: Current Opinion in Neurology, Stroke, Seizure, Cephalgia, Brain Injury more

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Neurology - Basic Science/Genetics News & Articles

Articles

Clinical Pearls in Neurology

Highlights in Neurology

Trans fat intake increases risk of ischemic stroke

New risk factors for chronic migraine identified

Ginsenoside-Rd improves outcomes in patients with acute ischemic stroke

Most Popular Neurology Articles

Other Topics in Neurology