What’s your first-line option for current Neurology information? MDLinx Neurology! Where else but MDLinx Neurology will you find subspecialty coverage of articles published on dementia, headache, movement disorders, neurologic oncology, neurosensory disorders, neurosurgery, pain medicine, pediatric neurology, sleep, spine and more? Also discover the latest clinical pearls from the Smartest Neurologist daily quiz competition and Neurology Physician Review. In less than five minutes a day, you can skim the summaries of pertinent articles within 24 hours of publication. Do you need the 2-minute update? Skip to the highlights from our physician editor, D. Scott Cunningham, MD, PhD, for the “can’t miss” summaries on hot topics in neurology and related subspecialties.
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1 Curcumin acts anti-proliferative and pro-apoptotic in human meningiomas Journal of Neuro-Oncology, May 24, 2013 Clinical Article
2 Expression of the G-CSF receptor, CD114, marks a novel, highly tumorigenic cell population in a neuroblastoma cell line Cancer Research, May 24, 2013 Clinical Article
3 ADAR2 editing activity in newly diagnosed versus relapsed pediatric high-grade astrocytomas Full Text BMC Cancer, May 24, 2013 Clinical Article
4 A simple electrodiagnostic method for morton neuroma Muscle & Nerve, May 24, 2013 Review Article
5 Prognostic value of residual fluorescent tissue in glioblastoma patients after gross total resection in 5-aminolevulinic acid-guided surgery Neurosurgery, May 24, 2013 Review Article
6 The antipsychotic agent chlorpromazine induces autophagic cell death by inhibiting Akt/mTOR pathway in human U-87MG glioma cells Carcinogenesis, May 24, 2013 Review Article
7 Mood disturbance in glioma patients Journal of Neuro-Oncology, May 23, 2013 Clinical Article
8 Long-term cognitive function, neuroimaging, and quality of life in primary CNS lymphoma Neurology, May 23, 2013 Clinical Article
9 β-blockers increase response to chemotherapy via direct antitumour and anti-angiogenic mechanisms in neuroblastoma British Journal of Cancer, May 23, 2013 Clinical Article
10 MR perfusion in and around the contrast-enhancement of primary CNS lymphomas Journal of Neuro-Oncology, May 23, 2013 Clinical Article
11 Defining pseudoprogression in glioblastoma multiforme European Journal of Neurology, May 23, 2013 Review Article
12 Blood-based biomarkers for malignant gliomas Journal of Neuro-Oncology, May 23, 2013 Clinical Article
13 Pathologic and gene expression features of metastatic melanomas to the brain Cancer, May 23, 2013 Review Article
14 GRIM-19 opposes reprogramming of glioblastoma cell metabolism via HIF1{alpha} destabilization Carcinogenesis, May 23, 2013 Clinical Article
15 Refined brain tumor diagnostics and stratified therapies: the requirement for a multidisciplinary approach Acta Neuropathologica, May 23, 2013 Review Article
16 Prognostic role for diffusion-weighted imaging of pediatric optic pathway glioma Journal of Neuro-Oncology, May 23, 2013 Clinical Article
17 Health-related quality of life in patients with brain tumors: limitations and additional outcome measures Current Neurology and Neuroscience Reports, May 22, 2013 Clinical Article
18 The expression of cytoglobin as a prognostic factor in gliomas: a retrospective analysis of 88 patients Full Text BMC Cancer, May 22, 2013 Clinical Article
19 Anticancer activity of tolfenamic acid in medulloblastoma: a preclinical study Tumor Biology, May 22, 2013 Clinical Article
20 Downregulation of miR-452 Promotes Stem-like traits and Tumorigenicity of Gliomas Clinical Cancer Research, May 22, 2013 Review Article
In a study involving 87,025 postmenopausal women in the Women’s Health Initiative Observational Study, there were 1049 incident cases of ischemic stroke over 663,041 person-years of follow-up. Women in the highest quintile of trans fat intake were at increased risk of ischemic stroke (HR = 1.39) compared with women in the lowest quintile of trans fat intake. Aspirin use modulated the effect of trans fats; ASA users and ASA non-users had HRs for ischemic stroke of 0.95 and 1.66, respectively. Saturated, monounsaturated, and polyunsaturated fat intake were not associated with ischemic stroke.
Read the article summaryAs published in the Journal of Neurological Sciences, increase tea consumption (> 4 cups/d), and diet consisting of hot and spicy foods, and weight gain increase the likelihood of chronicity in patients with episodic migraines. During a 12-month prospective study involving 188 patients with episodic migraines, 17.7% developed chronic, daily migraines. Other risk factors included low education, a high frequency of headaches, headaches of long duration, allodynia, and increased symptomatic treatment of headaches.
Read the article summaryIn a randomized, double-blind, placebo-controlled trial, the calcium channel antagonist, ginsenoside-Rd, has been shown to improve functional outcomes in patients (n=386) with acute ischemic strokes. The patients received a 14-day infusion of ginsenoside-Rd within 72 hours of stroke onset. The National Institutes of Health Stroke Score was improved at 15 days and the modified Rankin score was improved at 90 days (OR = 1.74).
Read the article summary1 Molecular Pathways: Radiation-Induced Cognitive Impairment Clinical Cancer Research, April 2, 2013 Review Article
2 Gliomatosis cerebri: clinical characteristics, management, and outcomes Journal of Neuro-Oncology, March 28, 2013 Review Article
3 Bevacizumab and Glioblastoma Multiforme: A Thrombosis and Bleeding Dilemma American Journal of Therapeutics, April 22, 2013 Review Article
4 Phase II Study of Bevacizumab and Temsirolimus Combination Therapy for Recurrent Glioblastoma Multiforme Anticancer Research, April 9, 2013
5 Probabilistic Radiographic Atlas of Glioblastoma Phenotypes American Journal of Neuroradiology, April 4, 2013
6 Levodopa/Carbidopa to Improve Motor Function Subsequent to Brain Tumor Excision American Journal of Physical Medicine & Rehabilitation, April 1, 2013
7 Isoflurane and sevoflurane increase interleukin-6 levels through the nuclear factor-kappa B pathway in neuroglioma cells British Journal of Anesthesia, April 23, 2013
8 Snail depletes the tumorigenic potential of glioblastoma Oncogene, April 9, 2013
9 Bevacizumab rescue therapy extends the survival in patients with recurrent malignant glioma Chinese Journal of Cancer Research, April 16, 2013 Free full text
10 Resting-state magnetoencephalography study of “small world” characteristics and cognitive dysfunction in patients with glioma OncoTargets and Therapy, April 5, 2013 Free full text
11 MicroRNAs involved in chemo- and radioresistance of high-grade gliomas Tumor Biology, April 19, 2013
12 Outcomes for patients with anaplastic astrocytoma treated with chemoradiation, radiation therapy alone or radiation therapy followed by chemotherapy: a retrospective review within the era of temozolomide Journal of Neuro-Oncology, March 26, 2013 Review Article
13 Modulation of the Wnt/beta-catenin pathway in human oligodendroglioma cells by Sox17 regulates proliferation and differentiation Cancer Letters, April 2, 2013
14 Brain metastases from papillary thyroid carcinomas Virchows Archiv, April 5, 2013
15 Assessing fitness to drive in brain tumour patients: a grey matter of law, ethics, and medicine Current Oncology, April 8, 2013 Free full text Review Article
16 Efficacy and safety of second-line fotemustine in elderly patients with recurrent glioblastoma Journal of Neuro-Oncology, April 12, 2013
17 Brain and Neck Tumors Among Physicians Performing Interventional Procedures The American Journal of Cardiology, April 29, 2013
18 Rare cell capture technology for the diagnosis of leptomeningeal metastasis in solid tumors Neurology, April 9, 2013
19 Surgical navigation-assisted endoscopic biopsy is feasible for safe and reliable diagnosis of unresectable solid brain tumors Neurosurgical Review, April 11, 2013 Review Article
20 A new prognostic scoring scale for patients with primary WHO grade III gliomas based on molecular predictors Journal of Neuro-Oncology, February 15, 2013
Indexed Journals in Neurology: Current Opinion in Neurology, Stroke, Seizure, Cephalgia, Brain Injury more
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