Neurology - Neurologic Oncology News & Articles

What’s your first-line option for current Neurology information? MDLinx Neurology! Where else but MDLinx Neurology will you find subspecialty coverage of articles published on dementia, headache, movement disorders, neurologic oncology, neurosensory disorders, neurosurgery, pain medicine, pediatric neurology, sleep, spine and more? Also discover the latest clinical pearls from the Smartest Neurologist daily quiz competition and Neurology Physician Review. In less than five minutes a day, you can skim the summaries of pertinent articles within 24 hours of publication. Do you need the 2-minute update? Skip to the highlights from our physician editor, D. Scott Cunningham, MD, PhD, for the “can’t miss” summaries on hot topics in neurology and related subspecialties.

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Latest (10) Full Text Articles (172) Focus on Neuromuscular Diseases

Ranked, sorted, and summarized by MDLinx editors from the latest literature

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161 Ex Vivo Activation of CD56+ Immune Cells That Eradicate Neuroblastoma Cancer Research, April 19, 2013 Clinical Article

162 Organotypic slice cultures of human glioblastoma reveal different susceptibilities to treatments Neuro-Oncology, April 18, 2013 Clinical Article

163 Phase I trial of capecitabine rapidly disintegrating tablets and concomitant radiation therapy in children with newly diagnosed brainstem gliomas and high-grade gliomas Neuro-Oncology, April 18, 2013 Review Article

164 Treating brain tumor-initiating cells using a combination of myxoma virus and rapamycin Neuro-Oncology, April 18, 2013 Review Article

165 Analysis of Treatment Outcomes of Intraventricular Chemotherapy in 105 Patients for Leptomeningeal Carcinomatosis from Non-Small-Cell Lung Cancer Journal of Thoracic Oncology, April 18, 2013 Clinical Article

166 De-repression of PDGFR{beta} transcription promotes acquired resistance to EGFR tyrosine kinase inhibitors in glioblastoma patients Cancer Discovery, April 18, 2013 Clinical Article

167 Elevated numbers of regulatory T cells, central memory T cells and class-switched B cells in cerebrospinal fluid of patients with anti-Hu antibody associated paraneoplastic neurological syndromes Journal of Neuroimmunology, April 18, 2013 Review Article

168 Spinal ependymomas: Prognostic factors and treatment results Journal of Cancer Research and Therapeutics, April 18, 2013 Clinical Article

169 Differential sensitivities of glioblastoma cell lines towards metabolic and signaling pathway inhibitions Cancer Letters, April 18, 2013 Clinical Article

170 Hypofractionated stereotactic radiotherapy for unifocal and multifocal recurrence of malignant gliomas Journal of Neuro-Oncology, April 18, 2013 Clinical Article

171 Diacylglycerol kinase alpha is a critical signaling node and novel therapeutic target in glioblastoma and other cancers Cancer Discovery, April 17, 2013 Clinical Article

172 Metabolic Mapping of Gliomas Using Hybrid MR-PET Imaging: Feasibility of the Method and Spatial Distribution of Metabolic Changes Investigative Radiology, April 17, 2013 Clinical Article

173 Radiation-induced TNFα cross signaling-dependent nuclear import of NFkB favors metastasis in neuroblastoma Clinical and Experimental Metastasis, April 17, 2013 Clinical Article

174 New Approaches to Understand Cognitive Changes Associated With Chemotherapy for Non-Central Nervous System Tumors Journal of Pain and Symptom Management, April 17, 2013 Review Article

175 Clinical significance of FOXP3 expression in human gliomas Clinical and Translational Oncology, April 17, 2013 Clinical Article

176 GRIM-19 Opposes Reprogramming of Glioblastoma Cell Metabolism via HIF1{alpha} Destabilization Carcinogenesis, April 17, 2013 Clinical Article

177 Dysembryoplastic neuroepithelial tumor, a pure glial tumor Neuropathology, April 17, 2013 Review Article

178 Bevacizumab rescue therapy extends the survival in patients with recurrent malignant glioma Full Text Chinese Journal of Cancer Research, April 16, 2013 Clinical Article

179 Tumor origin and growth pattern at diagnosis and surgical hypothalamic damage predict obesity in pediatric craniopharyngioma Journal of Neuro-Oncology, April 16, 2013 Clinical Article

180 Performance status during and after radiotherapy plus concomitant and adjuvant temozolomide in elderly patients with glioblastoma multiforme Journal of Clinical Neuroscience, April 16, 2013 Clinical Article

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Clinical Pearls in Neurology

Light-to-moderate alcohol consumption may be associated with a reduced risk of incident overall dementia and Alzheimer’s Disease
3 months’ topiramate therapy for migraine prophylaxis decreases waist circumference, abdominal skinfold measurements, and body fat ratio
For individuals with epilepsy, the risk having a broadly defined psychotic disorder is increased by 5.5-fold. The risk of having bipolar disorder is increased by 6.3-fold, and of having schizophrenia increases by 8.5-fold

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Highlights in Neurology

Trans fat intake increases risk of ischemic stroke

In a study involving 87,025 postmenopausal women in the Women’s Health Initiative Observational Study, there were 1049 incident cases of ischemic stroke over 663,041 person-years of follow-up. Women in the highest quintile of trans fat intake were at increased risk of ischemic stroke (HR = 1.39) compared with women in the lowest quintile of trans fat intake. Aspirin use modulated the effect of trans fats; ASA users and ASA non-users had HRs for ischemic stroke of 0.95 and 1.66, respectively. Saturated, monounsaturated, and polyunsaturated fat intake were not associated with ischemic stroke.

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New risk factors for chronic migraine identified

As published in the Journal of Neurological Sciences, increase tea consumption (> 4 cups/d), and diet consisting of hot and spicy foods, and weight gain increase the likelihood of chronicity in patients with episodic migraines. During a 12-month prospective study involving 188 patients with episodic migraines, 17.7% developed chronic, daily migraines. Other risk factors included low education, a high frequency of headaches, headaches of long duration, allodynia, and increased symptomatic treatment of headaches.

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Ginsenoside-Rd improves outcomes in patients with acute ischemic stroke

In a randomized, double-blind, placebo-controlled trial, the calcium channel antagonist, ginsenoside-Rd, has been shown to improve functional outcomes in patients (n=386) with acute ischemic strokes. The patients received a 14-day infusion of ginsenoside-Rd within 72 hours of stroke onset. The National Institutes of Health Stroke Score was improved at 15 days and the modified Rankin score was improved at 90 days (OR = 1.74).

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Most Popular Neurology Articles

Last month's top read Top Articles of 2012

1 Molecular Pathways: Radiation-Induced Cognitive Impairment Clinical Cancer Research, April 2, 2013 Review Article

2 Gliomatosis cerebri: clinical characteristics, management, and outcomes Journal of Neuro-Oncology, March 28, 2013 Review Article

3 Bevacizumab and Glioblastoma Multiforme: A Thrombosis and Bleeding Dilemma American Journal of Therapeutics, April 22, 2013 Review Article

4 Phase II Study of Bevacizumab and Temsirolimus Combination Therapy for Recurrent Glioblastoma Multiforme Anticancer Research, April 9, 2013

5 Probabilistic Radiographic Atlas of Glioblastoma Phenotypes American Journal of Neuroradiology, April 4, 2013

6 Levodopa/Carbidopa to Improve Motor Function Subsequent to Brain Tumor Excision American Journal of Physical Medicine & Rehabilitation, April 1, 2013

7 Isoflurane and sevoflurane increase interleukin-6 levels through the nuclear factor-kappa B pathway in neuroglioma cells British Journal of Anesthesia, April 23, 2013

8 Snail depletes the tumorigenic potential of glioblastoma Oncogene, April 9, 2013

9 Bevacizumab rescue therapy extends the survival in patients with recurrent malignant glioma Chinese Journal of Cancer Research, April 16, 2013 Free full text

10 Resting-state magnetoencephalography study of “small world” characteristics and cognitive dysfunction in patients with glioma OncoTargets and Therapy, April 5, 2013 Free full text

11 MicroRNAs involved in chemo- and radioresistance of high-grade gliomas Tumor Biology, April 19, 2013

12 Outcomes for patients with anaplastic astrocytoma treated with chemoradiation, radiation therapy alone or radiation therapy followed by chemotherapy: a retrospective review within the era of temozolomide Journal of Neuro-Oncology, March 26, 2013 Review Article

13 Modulation of the Wnt/beta-catenin pathway in human oligodendroglioma cells by Sox17 regulates proliferation and differentiation Cancer Letters, April 2, 2013

14 Brain metastases from papillary thyroid carcinomas Virchows Archiv, April 5, 2013

15 Assessing fitness to drive in brain tumour patients: a grey matter of law, ethics, and medicine Current Oncology, April 8, 2013 Free full text Review Article

16 Efficacy and safety of second-line fotemustine in elderly patients with recurrent glioblastoma Journal of Neuro-Oncology, April 12, 2013

17 Brain and Neck Tumors Among Physicians Performing Interventional Procedures The American Journal of Cardiology, April 29, 2013

18 Rare cell capture technology for the diagnosis of leptomeningeal metastasis in solid tumors Neurology, April 9, 2013

19 Surgical navigation-assisted endoscopic biopsy is feasible for safe and reliable diagnosis of unresectable solid brain tumors Neurosurgical Review, April 11, 2013 Review Article

20 A new prognostic scoring scale for patients with primary WHO grade III gliomas based on molecular predictors Journal of Neuro-Oncology, February 15, 2013

Indexed Journals in Neurology: Current Opinion in Neurology, Stroke, Seizure, Cephalgia, Brain Injury more

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Neurology - Neurologic Oncology News & Articles

Articles

Clinical Pearls in Neurology

Highlights in Neurology

Trans fat intake increases risk of ischemic stroke

New risk factors for chronic migraine identified

Ginsenoside-Rd improves outcomes in patients with acute ischemic stroke

Most Popular Neurology Articles

Other Topics in Neurology