What’s your first-line option for current Neurology information? MDLinx Neurology! Where else but MDLinx Neurology will you find subspecialty coverage of articles published on dementia, headache, movement disorders, neurologic oncology, neurosensory disorders, neurosurgery, pain medicine, pediatric neurology, sleep, spine and more? Also discover the latest clinical pearls from the Smartest Neurologist daily quiz competition and Neurology Physician Review. In less than five minutes a day, you can skim the summaries of pertinent articles within 24 hours of publication. Do you need the 2-minute update? Skip to the highlights from our physician editor, D. Scott Cunningham, MD, PhD, for the “can’t miss” summaries on hot topics in neurology and related subspecialties.
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1 The adoption of chronic fatigue syndrome/myalgic encephalomyelitis case definitions to assess prevalence: a systematic review Annals of Epidemiology , May 22, 2013 Evidence Based Medicine Review Article
2 First indigenous transmission of Japanese Encephalitis in urban areas of national capital territory of Delhi, India Tropical Medicine & International Health, May 22, 2013 Review Article Clinical Article
3 Pharmacodynamics of Liposomal Amphotericin B and Flucytosine for Cryptococcal Meningoencephalitis: Safe and Effective Regimens for Immunocompromised Patients The Journal of Infectious Diseases, May 21, 2013 Clinical Article
4 Analysis of plasma multiplex cytokines for children with febrile seizures and severe acute encephalitis Journal of Child Neurology, May 21, 2013 Clinical Article
5 T1-Weighted Dynamic Contrast-Enhanced MR Evaluation of Different Stages of Neurocysticercosis and Its Relationship with Serum MMP-9 Expression American Journal of Neuroradiology, May 21, 2013 Clinical Article
6 Replacement of Neisseria meningitidis C cc11/ET-15 variant by a cc103 hypervirulent clone, Brazil 2005-2011 Diagnostic Microbiology and Infectious Disease, May 21, 2013 Review Article
7 Prevalence and Outcomes of Cryptococcal Antigenemia in HIV-Seropositive Patients Hospitalized for Suspected Tuberculosis in Uganda Journal of Acquired Immune Deficiency Syndromes, May 21, 2013 Clinical Article
8 Laboratory evaluation of a rapid diagnostic test for Neisseria meningitidis serogroup A Transactions of the Royal Society of Tropical Medicine and Hygiene, May 21, 2013 Clinical Article
9 Correlative Imaging With 18F-FDG PET/CT and MRI in Paraneoplastic Limbic Encephalitis Clinical Nuclear Medicine , May 21, 2013
10 Flow Cytometric Assay Detecting Cytotoxicity against Human Endogenous Retrovirus Antigens Expressed on Cultured Multiple Sclerosis Cells Clinical and Experimental Immunology, May 20, 2013 Clinical Article
11 Diagnosis of tuberculosis infection based on synthetic peptides from Mycobacterium tuberculosis antigen 85 complex Clinical Neurology and Neurosurgery, May 17, 2013 Clinical Article
12 Congenital Lymphocytic Choriomeningitis Virus: When to Consider the Diagnosis Journal of Child Neurology, May 17, 2013 Clinical Article
13 Pharmacokinetics and Pharmacodynamics of Fluconazole for Cryptococcal Meningoencephalitis: Implications for Antifungal Therapy and In Vitro Susceptibility Breakpoints Antimicrobial Agents and Chemotherapy, May 17, 2013 Clinical Article
14 Tapeworm Infection of the Brain JAMA, May 16, 2013 Evidence Based Medicine Review Article Clinical Article
15 Single priming dose of meningococcal group C conjugate vaccine (NeisVac-C) in infants Vaccine , May 16, 2013 Clinical Article
16 Histidine-Rich Protein 2 Plasma Levels Predict Progression to Cerebral Malaria in Malawian Children With Plasmodium falciparum Infection The Journal of Infectious Diseases, May 16, 2013 Clinical Article
17 Rift Valley Fever Virus Clearance and Protection from Neurologic Disease Are Dependent on CD4+ T Cell and Virus-Specific Antibody Responses Journal of Virology, May 16, 2013 Review Article
18 Nervous System Lyme Disease: Diagnosis and Treatment Current Treatment Options in Neurology, May 15, 2013 Clinical Article
19 Herpes Simplex Encephalitis With Occipital Localization in an Infant: A Different Route of Entry in the Brain System Pediatric Neurology , May 15, 2013
20 Neurocysticercosis in Infants and Toddlers: Report of Seven Cases and Review of Published Patients Pediatric Neurology , May 15, 2013 Review Article
In a study involving 87,025 postmenopausal women in the Women’s Health Initiative Observational Study, there were 1049 incident cases of ischemic stroke over 663,041 person-years of follow-up. Women in the highest quintile of trans fat intake were at increased risk of ischemic stroke (HR = 1.39) compared with women in the lowest quintile of trans fat intake. Aspirin use modulated the effect of trans fats; ASA users and ASA non-users had HRs for ischemic stroke of 0.95 and 1.66, respectively. Saturated, monounsaturated, and polyunsaturated fat intake were not associated with ischemic stroke.
Read the article summaryAs published in the Journal of Neurological Sciences, increase tea consumption (> 4 cups/d), and diet consisting of hot and spicy foods, and weight gain increase the likelihood of chronicity in patients with episodic migraines. During a 12-month prospective study involving 188 patients with episodic migraines, 17.7% developed chronic, daily migraines. Other risk factors included low education, a high frequency of headaches, headaches of long duration, allodynia, and increased symptomatic treatment of headaches.
Read the article summaryIn a randomized, double-blind, placebo-controlled trial, the calcium channel antagonist, ginsenoside-Rd, has been shown to improve functional outcomes in patients (n=386) with acute ischemic strokes. The patients received a 14-day infusion of ginsenoside-Rd within 72 hours of stroke onset. The National Institutes of Health Stroke Score was improved at 15 days and the modified Rankin score was improved at 90 days (OR = 1.74).
Read the article summary1 Acute Encephalitis Critical Care Clinics, April 5, 2013 Review Article
2 Atypical Bickerstaff brainstem encephalitis: ataxic hypersomnolence without ophthalmoplegia Journal of Neurology, Neurosurgery & Psychiatry, April 11, 2013 Review Article
3 High-Density Lipoprotein: A Novel Marker for Risk of In-Hospital Infection in Acute Ischemic Stroke Patients Cerebrovascular Diseases, April 15, 2013
4
Neurobrucellosis: Clinical and Diagnostic Features
Clinical Infectious Diseases, April 29, 2013
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5 Cerebrospinal Fluid and Neuroimaging Biomarker Abnormalities Suggest Early Neurological Injury in a Subset of Individuals During Primary HIV Infection The Journal of Infectious Diseases, April 9, 2013
6 Anti-JC virus antibody prevalence in a multinational multiple sclerosis cohort Multiple Sclerosis Journal, April 1, 2013
7 Clinical Spectrum of Neurosyphilis among HIV-Negative Patients in the Modern Era Dermatology, April 19, 2013
8 Combination Antifungal Therapy for Cryptococcal Meningitis New England Journal of Medicine, April 8, 2013
9 De-escalation of antimicrobial treatment for adults with sepsis, severe sepsis or septic shock Cochrane Reviews, April 11, 2013 Review Article
10 Acute disseminated encephalomyelitis in conjunction with inflammatory bowel disease European Journal of Paediatric Neurology, March 7, 2013
11 The case for immunomodulatory approaches in treating HSV encephalitis Future Virology, March 14, 2013
12 Successful treatment of Epstein–Barr virus encephalitis in the setting of HIV-associated neurocognitive disorder: a diagnostic and therapeutic challenge Antiviral Therapy , April 1, 2013
13 Trends in the Management of Viral Meningitis at United States Children's Hospitals Pediatrics, April 3, 2013
14 CD8 Encephalitis in HIV-Infected Patients Receiving cART: A Treatable Entity Clinical Infectious Diseases, April 17, 2013
15 Long-term Outcomes of Congenital Cytomegalovirus Infection in Sweden and the United Kingdom Clinical Infectious Diseases, April 12, 2013
16 Varicella Zoster Virus Myelitis in Two Elderly Patients: Diagnostic Value of Nested Polymerase Chain Reaction Assay and Antibody Index for Cerebrospinal Fluid Specimens Case Reports in Neurology, April 12, 2013 Free full text
17 Skull base osteosarcoma presenting with cerebrospinal fluid leakage after CyberKnife(R) treatment: a case report Journal of Medical Case Reports, April 29, 2013 Free full text
18 Herpes simplex virus 2 meningitis: a retrospective cohort study Journal of NeuroVirology, March 21, 2013
19 Educational Achievement and Economic Self-sufficiency in Adults After Childhood Bacterial Meningitis Adult Functioning After Childhood Meningitis JAMA, April 25, 2013
20 Association of treatment for bacterial meningitis with the development of sequelae International Journal of Infectious Diseases, April 1, 2013
Indexed Journals in Neurology: Current Opinion in Neurology, Stroke, Seizure, Cephalgia, Brain Injury more
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