What’s your first-line option for current Neurology information? MDLinx Neurology! Where else but MDLinx Neurology will you find subspecialty coverage of articles published on dementia, headache, movement disorders, neurologic oncology, neurosensory disorders, neurosurgery, pain medicine, pediatric neurology, sleep, spine and more? Also discover the latest clinical pearls from the Smartest Neurologist daily quiz competition and Neurology Physician Review. In less than five minutes a day, you can skim the summaries of pertinent articles within 24 hours of publication. Do you need the 2-minute update? Skip to the highlights from our physician editor, D. Scott Cunningham, MD, PhD, for the “can’t miss” summaries on hot topics in neurology and related subspecialties.
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1 Criteria for mild cognitive impairment due to alzheimers disease in the community Annals of Neurology , May 22, 2013 Clinical Article
2 Vascular risk factors and neuropsychiatric symptoms in Alzheimers disease: the cache county study International Journal of Geriatric Psychiatry, May 22, 2013 Clinical Article
3 Epigenetic mechanisms in Alzheimer's disease: Implications for pathogenesis and therapy Ageing Research Reviews, May 22, 2013 Review Article
4 The influence of Apolipoprotein E genotype on regional pathology in Alzheimers disease Full Text BMC Neurology, May 22, 2013 Review Article
5 Awareness of deficits in alzheimers disease patients: Analysis of performance prediction discrepancies Psychiatry and Clinical Neurosciences, May 22, 2013 Clinical Article
6 Alzheimer Disease Alters the Relationship of Cardiorespiratory Fitness With Brain Activity During the Stroop Task Physical Therapy, May 22, 2013 Clinical Article
7 Effect of a multimodal exercise program on sleep disturbances and instrumental activities of daily living performance on Parkinsons and Alzheimers disease patients Geriatrics and Gerontology International, May 21, 2013 Clinical Article
8 Amyloidosis in Alzheimer's Disease: The Toxicity of Amyloid Beta (Aβ), Mechanisms of Its Accumulation and Implications of Medicinal Plants for Therapy Full Text Evidence-based Complementary and Alternative Medicine , May 21, 2013 Clinical Article
9 Fully-automated approach to hippocampus segmentation using a graph-cuts algorithm combined with atlas-based segmentation and morphological opening Magnetic Resonance Imaging, May 21, 2013 Clinical Article
10 Nature as a source of metabolites with cholinesterase-inhibitory activity: an approach to Alzheimers disease treatment Journal of Pharmacy and Pharmacology, May 21, 2013 Clinical Article
11 Drug development in dementia Maturitas, May 20, 2013 Clinical Article
12 Quality of life in patients with cognitive impairment: validation of the Quality of Life-Alzheimers Disease scale in Portugal International Psychogeriatrics, May 20, 2013 Clinical Article
13 Odor Identification Deficit Predicts Clinical Conversion from Mild Cognitive Impairment to Dementia Due to Alzheimers Disease Archives of Clinical Neurospsychology, May 20, 2013 Clinical Article
14 An Intervention to Enhance Alzheimers Disease Clinical Research Participation among Older African Americans Journal of Alzheimer’s Disease, May 20, 2013 Clinical Article
15 Interaction Between Two Cholesterol Metabolism Genes Influences Memory: Findings from the Wisconsin Registry for Alzheimers Prevention Journal of Alzheimer’s Disease, May 20, 2013 Review Article
16 Alterations in the Nuclear Architecture Produced by the Overexpression of Tau Protein in Neuroblastoma Cells Journal of Alzheimer’s Disease, May 20, 2013 Review Article
17 Association Between Interleukin 6 Gene Haplotype and Alzheimers Disease: A Brazilian Case-Control Study Journal of Alzheimer’s Disease, May 20, 2013 Review Article
18 CERAD test performance and cognitive impairment in Parkinsons disease Acta Neurologica Scandinavica, May 17, 2013 Clinical Article
19 Cognitive decline in Dravet syndrome: Is there a cerebellar role Epilepsy Research, May 17, 2013 Clinical Article
20 LDL Phenotype in Subjects with Mild Cognitive Impairment and Alzheimers Disease Journal of Alzheimer’s Disease, May 17, 2013 Clinical Article
In a study involving 87,025 postmenopausal women in the Women’s Health Initiative Observational Study, there were 1049 incident cases of ischemic stroke over 663,041 person-years of follow-up. Women in the highest quintile of trans fat intake were at increased risk of ischemic stroke (HR = 1.39) compared with women in the lowest quintile of trans fat intake. Aspirin use modulated the effect of trans fats; ASA users and ASA non-users had HRs for ischemic stroke of 0.95 and 1.66, respectively. Saturated, monounsaturated, and polyunsaturated fat intake were not associated with ischemic stroke.
Read the article summaryAs published in the Journal of Neurological Sciences, increase tea consumption (> 4 cups/d), and diet consisting of hot and spicy foods, and weight gain increase the likelihood of chronicity in patients with episodic migraines. During a 12-month prospective study involving 188 patients with episodic migraines, 17.7% developed chronic, daily migraines. Other risk factors included low education, a high frequency of headaches, headaches of long duration, allodynia, and increased symptomatic treatment of headaches.
Read the article summaryIn a randomized, double-blind, placebo-controlled trial, the calcium channel antagonist, ginsenoside-Rd, has been shown to improve functional outcomes in patients (n=386) with acute ischemic strokes. The patients received a 14-day infusion of ginsenoside-Rd within 72 hours of stroke onset. The National Institutes of Health Stroke Score was improved at 15 days and the modified Rankin score was improved at 90 days (OR = 1.74).
Read the article summary1 Inhaled Sevoflurane May Promote Progression of Amnestic Mild Cognitive Impairment: A Prospective, Randomized Parallel-Group Study The American Journal of the Medical Sciences, April 23, 2013
2 The safety and tolerability of rotigotine transdermal system over a 6-year period in patients with early-stage Parkinsons disease Journal of Neural Transmission, April 9, 2013
3 Identification of Resting and Active State EEG Features of Alzheimers Disease using Discrete Wavelet Transform Annals of Biomedical Engineering, April 15, 2013
4 Early Dementia Questionnaire (EDQ): a new screening instrument for early dementia in primary care practice BMC Family Practice, April 16, 2013 Free full text
5 Dietary patterns and risk of dementia in an elderly Japanese population: the Hisayama Study American Journal of Clinical Nutrition, April 5, 2013 Review Article
6 Predictors of Progression from Mild Cognitive Impairment to Dementia in the Placebo-Arm of a Clinical Trial Population Journal of Alzheimer’s Disease, April 24, 2013
7 A randomized, double-blind, placebo-controlled trial of memantine in a behaviorally enriched sample of patients with moderate-to-severe Alzheimers disease International Psychogeriatrics, April 23, 2013
8 Twenty-year changes in dementia occurrence suggest decreasing incidence in central Stockholm, Sweden Neurology, April 19, 2013
9 The Pattern of Diffusion Parameter Changes in Alzheimers Disease, Identified by Means of Linked Independent Component Analysis Journal of Alzheimer’s Disease, April 22, 2013
10 Higher serum glucose levels are associated with cerebral hypometabolism in Alzheimer regions Neurology, April 17, 2013
11 A Meta-Analysis of the Efficacy of Donepezil, Rivastigmine, Galantamine, and Memantine in Relation to Severity of Alzheimers Disease Journal of Alzheimer’s Disease, March 5, 2013 Evidence Based Medicine
12 Pharmacotherapeutic Management of Dementia Across Settings of Care Journal of the American Geriatrics Society, April 18, 2013
13 Diabetes mellitus and risk of dementia: A meta-analysis of prospective observational studies Journal of Diabetes Investigation, April 29, 2013 Evidence Based Medicine Review Article
14 Potentially inappropriate medication use among patients with Alzheimer disease in the REAL.FR cohort: be aware of atropinic and benzodiazepine drugs! European Journal of Clinical Pharmacology, April 26, 2013
15 Lifestyle change and the prevention of cognitive decline and dementia: what is the evidence? Current Opinion in Psychiatry, March 27, 2013
16 A review of brief cognitive assessment tests Reviews in Clinical Gerontology, April 26, 2013 Review Article
17 Prevalence and severity of behavioral and psychological symptoms of dementia (BPSD) in community dwelling Chinese: findings from the Shanghai three districts study Aging and Mental Health, April 8, 2013
18 Cognitive correlates of negative symptoms in behavioral variant frontotemporal dementia: implications for the frontal lobe syndrome Neurological Sciences, April 3, 2013
19 Visual Acuity in Institutionalized Seniors With Moderate to Severe Dementia Journal of the American Medical Directors Association, April 4, 2013 Review Article
20 The Cost-Effectiveness of the Decision to Hospitalize Nursing Home Residents With Advanced Dementia Journal of Pain and Symptom Management, April 12, 2013 Review Article
Indexed Journals in Neurology: Current Opinion in Neurology, Stroke, Seizure, Cephalgia, Brain Injury more
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