What’s your first-line option for current Neurology information? MDLinx Neurology! Where else but MDLinx Neurology will you find subspecialty coverage of articles published on dementia, headache, movement disorders, neurologic oncology, neurosensory disorders, neurosurgery, pain medicine, pediatric neurology, sleep, spine and more? Also discover the latest clinical pearls from the Smartest Neurologist daily quiz competition and Neurology Physician Review. In less than five minutes a day, you can skim the summaries of pertinent articles within 24 hours of publication. Do you need the 2-minute update? Skip to the highlights from our physician editor, D. Scott Cunningham, MD, PhD, for the “can’t miss” summaries on hot topics in neurology and related subspecialties.
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21 A novel bedside task to tap inhibitory dysfunction and fronto-striatal atrophy in Parkinsons disease Parkinsonism & Related Disorders, May 17, 2013 Clinical Article
22 Substantia nigra echogenicity is correlated with nigrostriatal impairment in Machado-Joseph disease Parkinsonism & Related Disorders, May 17, 2013 Clinical Article
23 Mesencephalic area measured by transcranial sonography in the differential diagnosis of parkinsonism Parkinsonism & Related Disorders, May 17, 2013 Clinical Article
24 Motor outcomes during hospitalization in Parkinsons disease patients: A prospective study Parkinsonism & Related Disorders, May 17, 2013 Clinical Article
25 Movement disorders and the osmotic demyelination syndrome Parkinsonism & Related Disorders, May 17, 2013 Review Article
26 CERAD test performance and cognitive impairment in Parkinsons disease Acta Neurologica Scandinavica, May 17, 2013 Clinical Article
27 The floating door sign in Parkinsons disease Parkinsonism & Related Disorders, May 17, 2013 Clinical Article
28 Somatic alpha-synuclein mutations in Parkinsons disease: Hypothesis and preliminary data Movement Disorders, May 17, 2013 Clinical Article
29 Prevalence of non motor features in a cohort of Parkinsons disease patients Clinical Neurology and Neurosurgery, May 17, 2013 Clinical Article
30 Pharmacokinetic Considerations for the Use of Levodopa in the Treatment of Parkinson Disease: Focus on Levodopa/Carbidopa/Entacapone for Treatment of Levodopa-Associated Motor Complications Clinical Neuropharmacology, May 16, 2013 Clinical Article
31 Pharmacologic Treatment of Anxiety Disorders in Parkinson Disease The American Journal of Geriatric Psychiatry, May 16, 2013 Clinical Article
32 Nicotine from edible Solanaceae and risk of Parkinson disease Annals of Neurology , May 16, 2013 Review Article
33
Could Sensory Mechanisms Be a Core Factor That Underlies Freezing of Gait in Parkinson's Disease?
PLOS ONE, May 16, 2013
Review Article
Exclusive Author Commentary
34 SNCA: Major genetic modifier of age at onset of Parkinsons disease Movement Disorders, May 16, 2013 Clinical Article
35 Factors predictive of the development of levodopa-induced dyskinesia and wearing-off in Parkinsons disease Movement Disorders, May 16, 2013 Clinical Article
36 Longitudinal assessment of tau and amyloid beta in cerebrospinal fluid of Parkinson disease Acta Neuropathologica, May 16, 2013 Clinical Article
37 Ocular tremor in Parkinsons disease: The debate is not over Movement Disorders, May 16, 2013 Clinical Article
38 Diffusion tensor imaging of Parkinsons disease, atypical parkinsonism, and essential tremor Movement Disorders, May 16, 2013 Clinical Article
39 Variability in neuronal expression of dopamine receptors and transporters in the substantia nigra Movement Disorders, May 16, 2013 Clinical Article
40 The many faces of alpha-synuclein mutations Movement Disorders, May 16, 2013 Clinical Article
In a study involving 87,025 postmenopausal women in the Women’s Health Initiative Observational Study, there were 1049 incident cases of ischemic stroke over 663,041 person-years of follow-up. Women in the highest quintile of trans fat intake were at increased risk of ischemic stroke (HR = 1.39) compared with women in the lowest quintile of trans fat intake. Aspirin use modulated the effect of trans fats; ASA users and ASA non-users had HRs for ischemic stroke of 0.95 and 1.66, respectively. Saturated, monounsaturated, and polyunsaturated fat intake were not associated with ischemic stroke.
Read the article summaryAs published in the Journal of Neurological Sciences, increase tea consumption (> 4 cups/d), and diet consisting of hot and spicy foods, and weight gain increase the likelihood of chronicity in patients with episodic migraines. During a 12-month prospective study involving 188 patients with episodic migraines, 17.7% developed chronic, daily migraines. Other risk factors included low education, a high frequency of headaches, headaches of long duration, allodynia, and increased symptomatic treatment of headaches.
Read the article summaryIn a randomized, double-blind, placebo-controlled trial, the calcium channel antagonist, ginsenoside-Rd, has been shown to improve functional outcomes in patients (n=386) with acute ischemic strokes. The patients received a 14-day infusion of ginsenoside-Rd within 72 hours of stroke onset. The National Institutes of Health Stroke Score was improved at 15 days and the modified Rankin score was improved at 90 days (OR = 1.74).
Read the article summary1 Rotigotine and specific non-motor symptoms of Parkinsons disease: Post hoc analysis of RECOVER Parkinsonism & Related Disorders, April 5, 2013
2 Prescription of drugs with potential adverse effects on cardiac conduction in Parkinsons disease Parkinsonism & Related Disorders, April 12, 2013
3 The relationship between balance control and vitamin D in Parkinsons disease--a pilot study Movement Disorders, April 11, 2013
4
Clinical utility of dopamine transporter single photon emission CT (DaT-SPECT) with (
5 Is cardiac function impaired in premotor Parkinsons disease- A retrospective cohort study Movement Disorders, April 1, 2013 Review Article
6 Long-term safety and efficacy of preladenant in subjects with fluctuating Parkinsons disease Movement Disorders, April 26, 2013
7 MR-guided focused ultrasound thalamotomy for essential tremor: a proof-of-concept study The Lancet Neurology, April 22, 2013
8 A two-year randomized controlled trial of progressive resistance exercise for Parkinsons disease Movement Disorders, April 16, 2013
9 Randomized, double-blind, placebo-controlled trial of vitamin D supplement in Parkinson's disease American Journal of Clinical Nutrition, March 15, 2013
10 Drug-induced dyskinesia in Parkinson's disease. Should success in clinical management be a function of improvement of motor repertoire rather than amplitude of dyskinesia? BMC Medicine, March 26, 2013 Free full text
11 Acute and chronic cognitive effects of levodopa and dopamine agonists in patients with Parkinsons disease:a review Therapeutic Advances in Psychopharmacology, March 4, 2013 Review Article
12 Peripheral neuropathy in Parkinsons disease: Levodopa exposure and implications for duodenal delivery Parkinsonism & Related Disorders, March 22, 2013
13 Often overlooked neuropsychiatric syndromes in Parkinson's disease British Journal of Medical Practitioners, April 12, 2013 Free full text Review Article
14 Changing the research criteria for the diagnosis of Parkinson's disease: obstacles and opportunities The Lancet Neurology, April 24, 2013
15 Robot-assisted gait training versus equal intensity treadmill training in patients with mild to moderate Parkinsons disease: A randomized controlled trial Parkinsonism & Related Disorders, April 2, 2013
16 Gray matter atrophy distinguishes between Parkinson disease motor subtypes Neurology, April 10, 2013 Review Article
17 A new paradigm for the management of essential vocal tremor with botulinum toxin The Laryngoscope, April 15, 2013
18 Inhaled dry powder apomorphine (VR040) for off periods in Parkinsons disease: an in-clinic double-blind dose ranging study Acta Neurologica Scandinavica, April 15, 2013
19 Multiscale Entropy Analysis of Electroencephalography During Sleep in Patients With Parkinson Disease Clinical EEG and Neuroscience, April 23, 2013
20 Attenuated neural response to gamble outcomes in drug-naive patients with Parkinsons disease Brain, April 4, 2013 Review Article
Indexed Journals in Neurology: Current Opinion in Neurology, Stroke, Seizure, Cephalgia, Brain Injury more
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