What’s your first-line option for current Neurology information? MDLinx Neurology! Where else but MDLinx Neurology will you find subspecialty coverage of articles published on dementia, headache, movement disorders, neurologic oncology, neurosensory disorders, neurosurgery, pain medicine, pediatric neurology, sleep, spine and more? Also discover the latest clinical pearls from the Smartest Neurologist daily quiz competition and Neurology Physician Review. In less than five minutes a day, you can skim the summaries of pertinent articles within 24 hours of publication. Do you need the 2-minute update? Skip to the highlights from our physician editor, D. Scott Cunningham, MD, PhD, for the “can’t miss” summaries on hot topics in neurology and related subspecialties.
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941 Patients with psychogenic non-epileptic seizures referred to a tertiary epilepsy centre: Patient characteristics in relation to diagnostic delay Clinical Neurology and Neurosurgery, March 21, 2012
942 Clinical epidemiology of posttraumatic epilepsy in a group of Chinese patients Seizure - European Journal of Epilepsy, March 21, 2012
943 Focal epilepsies in adult patients attending two epilepsy centers: Classification of drug-resistance, assessment of risk factors, and usefulness of new antiepileptic drugs Epilepsia, March 20, 2012 Clinical Article
944 Altered resting-state connectivity during interictal generalized spike-wave discharges in drug-naive childhood absence epilepsy Human Brain Mapping, March 20, 2012
945 Rufinamide as an adjuvant treatment in children with Lennox-Gastaut syndrome Seizure - European Journal of Epilepsy, March 19, 2012 Clinical Article
946 A meta-analysis of white matter changes in temporal lobe epilepsy as studied with diffusion tensor imaging Epilepsia, March 19, 2012
947 Onset of intractability and its course over time: The Dutch study of epilepsy in childhood Epilepsia, March 19, 2012
948 Cerebral blood flow and fMRI BOLD auditory language activation in temporal lobe epilepsy Epilepsia, March 19, 2012
949 Coexistence of schizophrenia and epilepsy: Record-linkage studies Epilepsia, March 16, 2012
950 Anaesthesia and epilepsy Full Text British Journal of Anesthesia, March 16, 2012
951 E-mail management of the modified Atkins Diet for adults with epilepsy is feasible and effective Epilepsia, March 16, 2012
952 Epilepsy in Tanzanian children: Association with perinatal events and other risk factors Epilepsia, March 16, 2012
953 Spatial MEG Laterality maps for language: Clinical applications in epilepsy Human Brain Mapping, March 16, 2012
954 Long-term seizure outcome and risk factors for recurrence after extratemporal epilepsy surgery Epilepsia, March 16, 2012
955 Impaired object identification in idiopathic childhood occipital epilepsy Epilepsia, March 14, 2012
956 Brain plasticity for verbal and visual memories in patients with mesial temporal lobe epilepsy and hippocampal sclerosis: An fMRI study Human Brain Mapping, March 13, 2012
957 Risk of seizures during intraoperative electrocortical stimulation of brain motor areas: a retrospective study on 50 patients Neurological Sciences, March 13, 2012
958 Elevated serum Bcl-2 in children with temporal lobe epilepsy Seizure - European Journal of Epilepsy, March 13, 2012
959 Ictal epileptic headache as subtle symptom in generalized idiopathic epilepsy Epilepsia, March 12, 2012
960 Defective visual inhibition in photosensitive idiopathic generalized epilepsy Epilepsia, March 12, 2012
In a study involving 87,025 postmenopausal women in the Women’s Health Initiative Observational Study, there were 1049 incident cases of ischemic stroke over 663,041 person-years of follow-up. Women in the highest quintile of trans fat intake were at increased risk of ischemic stroke (HR = 1.39) compared with women in the lowest quintile of trans fat intake. Aspirin use modulated the effect of trans fats; ASA users and ASA non-users had HRs for ischemic stroke of 0.95 and 1.66, respectively. Saturated, monounsaturated, and polyunsaturated fat intake were not associated with ischemic stroke.
Read the article summaryAs published in the Journal of Neurological Sciences, increase tea consumption (> 4 cups/d), and diet consisting of hot and spicy foods, and weight gain increase the likelihood of chronicity in patients with episodic migraines. During a 12-month prospective study involving 188 patients with episodic migraines, 17.7% developed chronic, daily migraines. Other risk factors included low education, a high frequency of headaches, headaches of long duration, allodynia, and increased symptomatic treatment of headaches.
Read the article summaryIn a randomized, double-blind, placebo-controlled trial, the calcium channel antagonist, ginsenoside-Rd, has been shown to improve functional outcomes in patients (n=386) with acute ischemic strokes. The patients received a 14-day infusion of ginsenoside-Rd within 72 hours of stroke onset. The National Institutes of Health Stroke Score was improved at 15 days and the modified Rankin score was improved at 90 days (OR = 1.74).
Read the article summary1 Calcium antagonists as an add-on therapy for drug-resistant epilepsy Cochrane Reviews, April 2, 2013 Review Article
2 Changing trends in the use of seizure prophylaxis after traumatic brain injury: A shift from phenytoin to levetiracetam Journal of Critical Care, April 9, 2013
3 Sulthiame add-on therapy for epilepsy Cochrane Reviews, April 5, 2013 Evidence Based Medicine
4 Intravenous topiramate: Safety and pharmacokinetics following a single dose in patients with epilepsy or migraines taking oral topiramate Epilepsia, April 22, 2013
5 Cardiopulmonary complications during pediatric seizures: A prelude to understanding SUDEP Epilepsia, April 11, 2013
6 A prospective multicenter comparison of levetiracetam versus phenytoin for early posttraumatic seizure prophylaxis The Journal of Trauma and Acute Care Surgery, March 4, 2013
7 The impact of methylphenidate on seizure frequency and severity in children with attention-deficit–hyperactivity disorder and difficult-to-treat epilepsies Developmental Medicine & Child Neurology, March 11, 2013
8 A pilot study assessing the bioavailability and pharmacokinetics of diazepam after intranasal and intravenous administration in healthy volunteers Epilepsy Research, April 16, 2013
9 Treatment of Status Epilepticus: An International Survey of Experts Neurocritical Care , March 26, 2013 Clinical Guideline
10 Early seizures after clipping of unruptured aneurysms of the anterior circulation: analysis on consecutive 1,000 cases Neurosurgical Review, April 10, 2013
11 Association of antibiotics with status epilepticus Neurological Sciences, March 7, 2013
12 Young adult ischaemic stroke related acute symptomatic and late seizures: risk factors European Journal of Neurology, April 17, 2013
13 Associations between particular types of fetal malformation and antiepileptic drug exposure in utero Acta Neurologica Scandinavica, March 26, 2013
14 Management of Status Epilepticus in Neurological Versus Medical Intensive Care Unit Neurocritical Care , April 17, 2013
15 Use of antiepileptics for seizure prophylaxis after traumatic brain injury American Journal of Health-System Pharmacy, April 22, 2013 Review Article
16 Electrode location and clinical outcome in hippocampal electrical stimulation for mesial temporal lobe epilepsy Seizure - European Journal of Epilepsy, April 1, 2013
17 Dravet syndrome patient-derived neurons suggest a novel epilepsy mechanism Annals of Neurology , March 26, 2013 Review Article
18 Complications of epilepsy surgery--a systematic review of focal surgical resections and invasive EEG monitoring Epilepsia, April 4, 2013
19 Effect of eslicarbazepine acetate on the pharmacokinetics of a combined ethinylestradiol/levonorgestrel oral contraceptive in healthy women Epilepsy Research, April 18, 2013
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Prevalence and subtypes of radiological cerebrovascular disease in late-onset isolated seizures and epilepsy
Clinical Neurology and Neurosurgery, April 15, 2013
Exclusive Author Commentary
Indexed Journals in Neurology: Current Opinion in Neurology, Stroke, Seizure, Cephalgia, Brain Injury more
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