Neurology News & Articles

What’s your first-line option for current Neurology information? MDLinx Neurology! Where else but MDLinx Neurology will you find subspecialty coverage of articles published on dementia, headache, movement disorders, neurologic oncology, neurosensory disorders, neurosurgery, pain medicine, pediatric neurology, sleep, spine and more? Also discover the latest clinical pearls from the Smartest Neurologist daily quiz competition and Neurology Physician Review. In less than five minutes a day, you can skim the summaries of pertinent articles within 24 hours of publication. Do you need the 2-minute update? Skip to the highlights from our physician editor, D. Scott Cunningham, MD, PhD, for the “can’t miss” summaries on hot topics in neurology and related subspecialties.

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Latest (54) Full Text Articles (2496) Focus on Seizures and Epilepsy

Ranked, sorted, and summarized by MDLinx editors from the latest literature

Topics:

1 Economic evaluation of percutaneous left atrial appendage occlusion, dabigatran, and warfarin for stroke prevention in patients with nonvalvular atrial fibrillation Circulation, June 19, 2013 Clinical Article

2 The University of Texas Houston Stroke Registry (UTHSR): implementation of enhanced data quality assurance procedures improves data quality Full Text BMC Neurology, June 19, 2013 Clinical Article

3 Diagnostic accuracy of CT perfusion imaging for detecting acute ischemic stroke: a systematic review and meta-analysis Cerebrovascular Diseases, June 19, 2013 Clinical Article

4 Elevated factor VIII level and stroke in patients without traditional risk factors associated with cardiovascular diseases Full Text Neuropsychiatric Disease and Treatment, June 19, 2013 Clinical Article

5 Effects of lacosamide and carbamazepine on human motor cortex excitability: A double-blind, placebo-controlled transcranial magnetic stimulation study Seizure - European Journal of Epilepsy, June 19, 2013 Clinical Article

6 Heart rate variability remains reduced and sympathetic tone elevated after temporal lobe epilepsy surgery Seizure - European Journal of Epilepsy, June 19, 2013 Clinical Article

7 ICTAL modulation of cardiac repolarization, but not of heart rate, is lateralized in mesial temporal lobe epilepsy PLOS ONE, June 19, 2013 Review Article

8 Hyperlipidemia attenuates vascular endothelial growth factor–induced angiogenesis, impairs cerebral blood flow, and disturbs stroke recovery via decreased pericyte coverage of brain endothelial cells Arteriosclerosis, Thrombosis, and Vascular Biology, June 19, 2013 Clinical Article

9 Bapineuzumab and solanezumab for Alzheimers disease: is the amyloid cascade hypothesis still alive? Expert Opinion on Biological Therapy, June 19, 2013 Review Article

10 Accurate multimodal probabilistic prediction of conversion to alzheimers disease in patients with mild cognitive impairment NeuroImage: Clinical, June 19, 2013 Clinical Article

11 Clinical features of late-onset partial cryptogenic epilepsy: Toward an idiopathic temporal epilepsy Epilepsy & Behavior, June 19, 2013 Review Article

12 Quality of end-of-life care of long-term nursing home residents with and without dementia Journal of the American Geriatrics Society, June 19, 2013 Review Article

13 Neuromyelitis optica and aquaporin-4 (AQP4) autoantibodies in consecutive optic neuritis patients in Southern Finland Acta Ophthalmologica, June 19, 2013 Review Article

14 Parkinsons disease genes do not segregate with breast cancer genes loci Cancer Epidemiology, Biomarkers & Prevention, June 19, 2013 Clinical Article

15 proMetalloproteinase-10 is associated with brain damage and clinical outcome in acute ischemic stroke Journal of Thrombosis and Haemostasis, June 19, 2013 Clinical Article

16 Intravenous immunoglobulin and Alzheimers disease: what now? Full Text Journal of Neuroinflammation, June 19, 2013 Review Article

17 Longitudinal effects of lesions on functional networks after stroke Journal of Cerebral Blood Flow & Metabolism, June 19, 2013 Review Article

18 Neural correlates of motor impairment during motor imagery and motor execution in sub-cortical stroke Brain Injury, June 19, 2013 Clinical Article

19 Tau clearance mechanisms and their possible role in the pathogenesis of Alzheimer disease Frontiers in Neurology, June 19, 2013 Review Article

20 Signal transduction in cerebral arteries after subarachnoid hemorrhage—a phosphoproteomic approach Journal of Cerebral Blood Flow & Metabolism, June 19, 2013 Review Article

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Clinical Pearls in Neurology

Light-to-moderate alcohol consumption may be associated with a reduced risk of incident overall dementia and Alzheimer’s Disease
3 months’ topiramate therapy for migraine prophylaxis decreases waist circumference, abdominal skinfold measurements, and body fat ratio
For individuals with epilepsy, the risk having a broadly defined psychotic disorder is increased by 5.5-fold. The risk of having bipolar disorder is increased by 6.3-fold, and of having schizophrenia increases by 8.5-fold

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Highlights in Neurology

Trans fat intake increases risk of ischemic stroke

In a study involving 87,025 postmenopausal women in the Women’s Health Initiative Observational Study, there were 1049 incident cases of ischemic stroke over 663,041 person-years of follow-up. Women in the highest quintile of trans fat intake were at increased risk of ischemic stroke (HR = 1.39) compared with women in the lowest quintile of trans fat intake. Aspirin use modulated the effect of trans fats; ASA users and ASA non-users had HRs for ischemic stroke of 0.95 and 1.66, respectively. Saturated, monounsaturated, and polyunsaturated fat intake were not associated with ischemic stroke.

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New risk factors for chronic migraine identified

As published in the Journal of Neurological Sciences, increase tea consumption (> 4 cups/d), and diet consisting of hot and spicy foods, and weight gain increase the likelihood of chronicity in patients with episodic migraines. During a 12-month prospective study involving 188 patients with episodic migraines, 17.7% developed chronic, daily migraines. Other risk factors included low education, a high frequency of headaches, headaches of long duration, allodynia, and increased symptomatic treatment of headaches.

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Ginsenoside-Rd improves outcomes in patients with acute ischemic stroke

In a randomized, double-blind, placebo-controlled trial, the calcium channel antagonist, ginsenoside-Rd, has been shown to improve functional outcomes in patients (n=386) with acute ischemic strokes. The patients received a 14-day infusion of ginsenoside-Rd within 72 hours of stroke onset. The National Institutes of Health Stroke Score was improved at 15 days and the modified Rankin score was improved at 90 days (OR = 1.74).

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Most Popular Neurology Articles

Last month's top read Top Articles of 2012

1 Aspirin nonresponders in patients with ischaemic stroke Blood Coagulation & Fibrinolysis, May 14, 2013

2 Effect of addition of clopidogrel to aspirin on stroke incidence: Meta-analysis of randomized trials International Journal of Stroke, May 23, 2013

3 Triple therapy with deferiprone, idebenone and riboflavin in Friedreich's ataxia – open-label trial Acta Neurologica Scandinavica, May 17, 2013

4 Treatment with statins and ischemic stroke severity Neurology, April 25, 2013

5 Effectiveness of antidementia drugs in delaying Alzheimers disease progression Alzheimer's & Dementia, May 2, 2013

6 Targeted use of heparin, heparinoids, or low-molecular-weight heparin to improve outcome after acute ischaemic stroke: an individual patient data meta-analysis of randomised controlled trials The Lancet Neurology, May 17, 2013 Evidence Based Medicine Review Article

7 Oxcarbazepine for neuropathic pain Cochrane Reviews, April 2, 2013 Review Article

8 The relationship between serum levels of vitamin D and migraine Journal of Research in Medical Sciences, March 12, 2013 Evidence Based Medicine

9 Cost-effectiveness of apixaban, dabigatran, rivaroxaban, and warfarin for stroke prevention in atrial fibrillation Stroke, May 29, 2013

10 Potential impact of new oral anticoagulants on the management of atrial fibrillation-related stroke in primary care International Journal of Clinical Practice, May 7, 2013

11 Operative mortality and stroke after on-pump vs off-pump surgery in high-risk patients: an analysis of 83 914 coronary bypass operations European Journal of Cardio-Thoracic Surgery, May 20, 2013

12 New Evidence for Therapies in Stroke Rehabilitation Current Atherosclerosis Reports, May 3, 2013 Evidence Based Medicine Review Article

13 The effects of long-term interferon- beta-1b treatment on cognitive functioning in multiple sclerosis: a 16-year longitudinal study Multiple Sclerosis Journal, May 10, 2013

14 Headaches during pregnancy Clinical Obstetrics and Gynecology, May 8, 2013

15 Atrial fibrillation in young stroke patients European Journal of Neurology, May 22, 2013

16 Aspirin with or without an antiemetic for acute migraine headaches in adults Cochrane Reviews, May 10, 2013 Evidence Based Medicine

17 Benefits of combined cholinesterase inhibitor and memantine treatment in moderate-severe Alzheimers disease Alzheimer's & Dementia, May 13, 2013 Review Article

18 Paracetamol (Acetaminophen) in stroke 2 (PAIS 2): Protocol for a randomized, placebo-controlled, double-blind clinical trial to assess the effect of high-dose paracetamol on functional outcome in patients with acute stroke and a body temperature of 36·5°C or above International Journal of Stroke, May 28, 2013

19 Inhaled Sevoflurane May Promote Progression of Amnestic Mild Cognitive Impairment: A Prospective, Randomized Parallel-Group Study The American Journal of the Medical Sciences, April 23, 2013

20 Dietary calcium intake and risk of stroke: a dose-response meta-analysis American Journal of Clinical Nutrition, April 5, 2013 Evidence Based Medicine

Indexed Journals in Neurology: Current Opinion in Neurology, Stroke, Seizure, Cephalgia, Brain Injury more

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Neurology News & Articles

Articles

Clinical Pearls in Neurology

Highlights in Neurology

Trans fat intake increases risk of ischemic stroke

New risk factors for chronic migraine identified

Ginsenoside-Rd improves outcomes in patients with acute ischemic stroke

Most Popular Neurology Articles

Other Topics in Neurology