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Neurology News & Articles
What’s your first-line option for current Neurology information? MDLinx Neurology! Where else but MDLinx Neurology will you find subspecialty coverage of articles published on dementia, headache, movement disorders, neurologic oncology, neurosensory disorders, neurosurgery, pain medicine, pediatric neurology, sleep, spine and more? Also discover the latest clinical pearls from the Smartest Neurologist daily quiz competition and Neurology Physician Review. In less than five minutes a day, you can skim the summaries of pertinent articles within 24 hours of publication. Do you need the 2-minute update? Skip to the highlights from our physician editor, D. Scott Cunningham, MD, PhD, for the “can’t miss” summaries on hot topics in neurology and related subspecialties.
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Articles
Latest (67) Full Text Articles (2496) Focus on Neuromuscular Diseases101 An uncommon case of random fire-setting behavior associated with Todd paralysis: A case report Full Text BMC Psychiatry, September 17, 2012
102 Effects of Age and Amyloid Deposition on Aβ Dynamics in the Human Central Nervous System Full Text Archives of Neurology, September 16, 2012 Original Publication Date: September 15, 2011
103 Cerebrospinal Fluid Biomarkers, Education, Brain Volume, and Future Cognitio Full Text Archives of Neurology, September 16, 2012 Original Publication Date: September 16, 2011
104 Association of Age at Diagnosis and Genetic Mutations in Patients With Neuroblastoma Full Text JAMA, September 16, 2012 Original Publication Date: March 15, 2012
105 Muscle Magnetic Resonance Imaging in Congenital Myopathies Due to Ryanodine Receptor Type 1 Gene Mutations Full Text Archives of Neurology, September 16, 2012 Original Publication Date: September 15, 2011
106 Second-line status epilepticus treatment: Comparison of phenytoin, valproate, and levetiracetam Full Text Epilepsia, September 15, 2012 Original Publication Date: April 14, 2011 Clinical Article
107 Rituximab-associated progressive multifocal leukoencephalopathy in rheumatoid arthritis Full Text Archives of Neurology, September 15, 2012 Original Publication Date: September 14, 2011 Clinical Article
108 Diffusion Tensor Imaging in Acute Optic Neuropathies: Predictor of Clinical Outcomes Full Text Archives of Neurology, September 15, 2012 Original Publication Date: September 14, 2011
109 Comparison of Analytical Platforms for Cerebrospinal Fluid Measures of β-Amyloid 1-42, Total tau, and P-tau181 for Identifying Alzheimer Disease Amyloid Plaque Pathology Full Text Archives of Neurology, September 15, 2012 Original Publication Date: September 14, 2011
110 Statins and Intracerebral Hemorrhage: A Retrospective Cohort Study Full Text Archives of Neurology, September 14, 2012 Original Publication Date: September 13, 2011 Clinical Article
111 Donepezil and Memantine for Moderate-to-Severe Alzheimers Disease Full Text New England Journal of Medicine, September 14, 2012 Original Publication Date: March 13, 2012 Clinical Article
112 Intranasal Insulin Therapy for Alzheimer Disease and Amnestic Mild Cognitive Impairment: A Pilot Clinical Trial Full Text Archives of Neurology, September 14, 2012 Original Publication Date: September 15, 2011 Clinical Article
113 Risk Factors and Preventive Interventions for Alzheimer Disease: State of the Science Full Text Archives of Neurology, September 14, 2012 Original Publication Date: September 13, 2011
114 Rationale and design of a double-blind, placebo-controlled, randomized trial to evaluate the safety and efficacy of nimodipine in preventing cognitive impairment in ischemic cerebrovascular events (NICE) Full Text BMC Neurology, September 14, 2012 Clinical Article
115 Assessing Response to Stroke Thrombolysis: Validation of 24-Hour Multimodal Magnetic Resonance Imaging Full Text Archives of Neurology, September 14, 2012 Original Publication Date: September 16, 2011 Clinical Article
116 Trajectories of Psychological Distress After Stroke Full Text Annals of Family Medicine, September 14, 2012
117 CMV-associated encephalitis and antineuronal autoantibodies - a case report Full Text BMC Neurology, September 14, 2012
118 Central poststroke pain: somatosensory abnormalities and the presence of associated myofascial pain syndrome Full Text BMC Neurology, September 13, 2012 Clinical Article
119 The Effect of Early Trauma Exposure on Serotonin Type 1B Receptor Expression Revealed by Reduced Selective Radioligand Binding Full Text Archives of General Psychiatry, September 13, 2012 Original Publication Date: September 13, 2011
120 Bmi-1 promotes the aggressiveness of glioma via activating the NF-kappaB/MMP-9 signaling pathway Full Text BMC Cancer, September 13, 2012
Clinical Pearls in Neurology
- Light-to-moderate alcohol consumption may be associated with a reduced risk of incident overall dementia and Alzheimer’s Disease
- 3 months’ topiramate therapy for migraine prophylaxis decreases waist circumference, abdominal skinfold measurements, and body fat ratio
- For individuals with epilepsy, the risk having a broadly defined psychotic disorder is increased by 5.5-fold. The risk of having bipolar disorder is increased by 6.3-fold, and of having schizophrenia increases by 8.5-fold
Highlights in Neurology
Trans fat intake increases risk of ischemic stroke
In a study involving 87,025 postmenopausal women in the Women’s Health Initiative Observational Study, there were 1049 incident cases of ischemic stroke over 663,041 person-years of follow-up. Women in the highest quintile of trans fat intake were at increased risk of ischemic stroke (HR = 1.39) compared with women in the lowest quintile of trans fat intake. Aspirin use modulated the effect of trans fats; ASA users and ASA non-users had HRs for ischemic stroke of 0.95 and 1.66, respectively. Saturated, monounsaturated, and polyunsaturated fat intake were not associated with ischemic stroke.
Read the article summaryNew risk factors for chronic migraine identified
As published in the Journal of Neurological Sciences, increase tea consumption (> 4 cups/d), and diet consisting of hot and spicy foods, and weight gain increase the likelihood of chronicity in patients with episodic migraines. During a 12-month prospective study involving 188 patients with episodic migraines, 17.7% developed chronic, daily migraines. Other risk factors included low education, a high frequency of headaches, headaches of long duration, allodynia, and increased symptomatic treatment of headaches.
Read the article summaryGinsenoside-Rd improves outcomes in patients with acute ischemic stroke
In a randomized, double-blind, placebo-controlled trial, the calcium channel antagonist, ginsenoside-Rd, has been shown to improve functional outcomes in patients (n=386) with acute ischemic strokes. The patients received a 14-day infusion of ginsenoside-Rd within 72 hours of stroke onset. The National Institutes of Health Stroke Score was improved at 15 days and the modified Rankin score was improved at 90 days (OR = 1.74).
Read the article summaryMost Popular Neurology Articles
Last month's top read Top Articles of 20121 Oxcarbazepine for neuropathic pain Cochrane Reviews, April 2, 2013 Review Article
2 Dietary calcium intake and risk of stroke: a dose-response meta-analysis American Journal of Clinical Nutrition, April 5, 2013 Evidence Based Medicine
3 The relationship between serum levels of vitamin D and migraine Journal of Research in Medical Sciences, March 12, 2013 Evidence Based Medicine
4 Association of statin use with risk of dementia: A meta-analysis of prospective cohort studies Geriatrics and Gerontology International, March 8, 2013 Evidence Based Medicine
5 National Institutes of Health Stroke Scale Score and Vessel Occlusion in 2152 Patients With Acute Ischemic Stroke Stroke, March 29, 2013
6 A Randomized Trial of Intravenous Ketorolac Versus Intravenous Metoclopramide Plus Diphenhydramine for Tension-Type and All Nonmigraine, Noncluster Recurrent Headaches Annals of Emergency Medicine, April 9, 2013
7 Dietary Fiber Intake and Risk of First Stroke Stroke, April 23, 2013
8 Efficacy and safety of dabigatran etexilate and warfarin in real world patients with atrial fibrillation: A prospective nationwide cohort study JACC - Journal of the American College of Cardiology, April 15, 2013
9 Novel oral anticoagulants for stroke prevention in atrial fibrillation: a focus on the older patient International Journal of General Medicine, April 11, 2013 Free full text
10 Treatment with statins and ischemic stroke severity Neurology, April 25, 2013
11 Statins Reduce Neurologic Injury in Asymptomatic Carotid Endarterectomy Patients Stroke, April 2, 2013
12 One-Year Progression of Moderate Asymptomatic Carotid Stenosis Predicts the Risk of Vascular Events Stroke, March 15, 2013
13 Use of Common Migraine Treatments in Breast-Feeding Women: A Summary of Recommendations Headache: The Journal of Head and Face Pain, March 28, 2013 Review Article
14 A prospective multicenter comparison of levetiracetam versus phenytoin for early posttraumatic seizure prophylaxis The Journal of Trauma and Acute Care Surgery, March 4, 2013
15 Risk of ischemic stroke with the use of risperidone, quetiapine and olanzapine in elderly patients: a population-based, case-crossover study Journal of Psychopharmacology, April 9, 2013
16 The Stroke Hyperglycemia Insulin Network Effort (SHINE) trial protocol: a randomized, blinded, efficacy trial of standard vs. intensive hyperglycemia management in acute stroke International Journal of Stroke, April 3, 2013
17 Inhaled Sevoflurane May Promote Progression of Amnestic Mild Cognitive Impairment: A Prospective, Randomized Parallel-Group Study The American Journal of the Medical Sciences, April 23, 2013
18 Coronary Artery Calcification Is an Independent Stroke Predictor in the General Population Stroke, April 5, 2013
19 Long-term Mortality After Stroke Among Adults Aged 18 to 50 Years JAMA, April 12, 2013
20 The obesity paradox in stroke: Lower mortality and lower risk of readmission for recurrent stroke in obese stroke patients International Journal of Stroke, March 22, 2013
Indexed Journals in Neurology: Current Opinion in Neurology, Stroke, Seizure, Cephalgia, Brain Injury more
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