What’s your first-line option for current Neurology information? MDLinx Neurology! Where else but MDLinx Neurology will you find subspecialty coverage of articles published on dementia, headache, movement disorders, neurologic oncology, neurosensory disorders, neurosurgery, pain medicine, pediatric neurology, sleep, spine and more? Also discover the latest clinical pearls from the Smartest Neurologist daily quiz competition and Neurology Physician Review. In less than five minutes a day, you can skim the summaries of pertinent articles within 24 hours of publication. Do you need the 2-minute update? Skip to the highlights from our physician editor, D. Scott Cunningham, MD, PhD, for the “can’t miss” summaries on hot topics in neurology and related subspecialties.
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61 A comprehensive next generation sequencing based genetic testing strategy to improve diagnosis of inherited pheochromocytoma and paraganglioma Journal of Clinical Endocrinology and Metabolism, May 17, 2013 Review Article
62 Mesencephalic area measured by transcranial sonography in the differential diagnosis of parkinsonism Parkinsonism & Related Disorders, May 17, 2013 Clinical Article
63 Motor outcomes during hospitalization in Parkinsons disease patients: A prospective study Parkinsonism & Related Disorders, May 17, 2013 Clinical Article
64 Movement disorders and the osmotic demyelination syndrome Parkinsonism & Related Disorders, May 17, 2013 Review Article
65 The physical anthropometry, lifestyle habits and blood pressure of people presenting with a first clinical demyelinating event compared to controls: The Ausimmune study Multiple Sclerosis Journal, May 17, 2013 Clinical Article
66 CERAD test performance and cognitive impairment in Parkinsons disease Acta Neurologica Scandinavica, May 17, 2013 Clinical Article
67 The floating door sign in Parkinsons disease Parkinsonism & Related Disorders, May 17, 2013 Clinical Article
68 Defining the epsilon-sarcoglycan (SGCE) gene phenotypic signature in myoclonus-dystonia: A reappraisal of genetic testing criteria Movement Disorders, May 17, 2013 Clinical Article
69 Somatic alpha-synuclein mutations in Parkinsons disease: Hypothesis and preliminary data Movement Disorders, May 17, 2013 Clinical Article
70 The chemokine receptor CCR5 Δ32 allele in natalizumab-treated multiple sclerosis Acta Neurologica Scandinavica, May 17, 2013 Clinical Article
71 Revisiting the role of systemic therapies in patients with metastatic melanoma to the CNS Expert Review of Anticancer Therapy, May 17, 2013 Clinical Article
72 Sympathetic Nervous System Function and Dysfunction in Chronic Hemodialysis Patients Seminars in Dialysis, May 17, 2013 Review Article Clinical Article
73 Differential effects of genetic susceptibility factors in males and females with multiple sclerosis Clinical Immunology, May 17, 2013 Review Article
74 The long pentraxin PTX3 as a correlate of cancer-related inflammation and prognosis of malignancy in gliomas Journal of Neuroimmunology, May 17, 2013 Clinical Article
75 Transitioning outcomes measures: relationship between the CMTPedS and CMTNSv2 in children, adolescents and young adults with Charcot-Marie-Tooth disease Journal of the Peripheral Nervous System, May 17, 2013 Clinical Article
76 TMS-EEG reveals impaired intracortical interactions and coherence in Unverricht-Lundborg type progressive myoclonus epilepsy (EPM1) Epilepsy Research, May 17, 2013 Clinical Article
77 Rapid onset of a kainate-induced mirror focus in rat hippocampus is mediated by contralateral AMPA receptors Epilepsy Research, May 17, 2013 Clinical Article
78 Cognitive decline in Dravet syndrome: Is there a cerebellar role Epilepsy Research, May 17, 2013 Clinical Article
79 Clinical Outcomes Following Prolonged Refractory Status Epilepticus (PRSE) Neurocritical Care , May 17, 2013 Clinical Article
80 Depression in patients with newly diagnosed epilepsy predicts lamotrigine-induced rash: A short-term observational study Epilepsy & Behavior, May 17, 2013 Clinical Article
In a study involving 87,025 postmenopausal women in the Women’s Health Initiative Observational Study, there were 1049 incident cases of ischemic stroke over 663,041 person-years of follow-up. Women in the highest quintile of trans fat intake were at increased risk of ischemic stroke (HR = 1.39) compared with women in the lowest quintile of trans fat intake. Aspirin use modulated the effect of trans fats; ASA users and ASA non-users had HRs for ischemic stroke of 0.95 and 1.66, respectively. Saturated, monounsaturated, and polyunsaturated fat intake were not associated with ischemic stroke.
Read the article summaryAs published in the Journal of Neurological Sciences, increase tea consumption (> 4 cups/d), and diet consisting of hot and spicy foods, and weight gain increase the likelihood of chronicity in patients with episodic migraines. During a 12-month prospective study involving 188 patients with episodic migraines, 17.7% developed chronic, daily migraines. Other risk factors included low education, a high frequency of headaches, headaches of long duration, allodynia, and increased symptomatic treatment of headaches.
Read the article summaryIn a randomized, double-blind, placebo-controlled trial, the calcium channel antagonist, ginsenoside-Rd, has been shown to improve functional outcomes in patients (n=386) with acute ischemic strokes. The patients received a 14-day infusion of ginsenoside-Rd within 72 hours of stroke onset. The National Institutes of Health Stroke Score was improved at 15 days and the modified Rankin score was improved at 90 days (OR = 1.74).
Read the article summary1 Oxcarbazepine for neuropathic pain Cochrane Reviews, April 2, 2013 Review Article
2 Dietary calcium intake and risk of stroke: a dose-response meta-analysis American Journal of Clinical Nutrition, April 5, 2013 Evidence Based Medicine
3 The relationship between serum levels of vitamin D and migraine Journal of Research in Medical Sciences, March 12, 2013 Evidence Based Medicine
4 Association of statin use with risk of dementia: A meta-analysis of prospective cohort studies Geriatrics and Gerontology International, March 8, 2013 Evidence Based Medicine
5 National Institutes of Health Stroke Scale Score and Vessel Occlusion in 2152 Patients With Acute Ischemic Stroke Stroke, March 29, 2013
6 A Randomized Trial of Intravenous Ketorolac Versus Intravenous Metoclopramide Plus Diphenhydramine for Tension-Type and All Nonmigraine, Noncluster Recurrent Headaches Annals of Emergency Medicine, April 9, 2013
7 Dietary Fiber Intake and Risk of First Stroke Stroke, April 23, 2013
8 Efficacy and safety of dabigatran etexilate and warfarin in real world patients with atrial fibrillation: A prospective nationwide cohort study JACC - Journal of the American College of Cardiology, April 15, 2013
9 Novel oral anticoagulants for stroke prevention in atrial fibrillation: a focus on the older patient International Journal of General Medicine, April 11, 2013 Free full text
10 Treatment with statins and ischemic stroke severity Neurology, April 25, 2013
11 Statins Reduce Neurologic Injury in Asymptomatic Carotid Endarterectomy Patients Stroke, April 2, 2013
12 One-Year Progression of Moderate Asymptomatic Carotid Stenosis Predicts the Risk of Vascular Events Stroke, March 15, 2013
13 Use of Common Migraine Treatments in Breast-Feeding Women: A Summary of Recommendations Headache: The Journal of Head and Face Pain, March 28, 2013 Review Article
14 A prospective multicenter comparison of levetiracetam versus phenytoin for early posttraumatic seizure prophylaxis The Journal of Trauma and Acute Care Surgery, March 4, 2013
15 Risk of ischemic stroke with the use of risperidone, quetiapine and olanzapine in elderly patients: a population-based, case-crossover study Journal of Psychopharmacology, April 9, 2013
16 The Stroke Hyperglycemia Insulin Network Effort (SHINE) trial protocol: a randomized, blinded, efficacy trial of standard vs. intensive hyperglycemia management in acute stroke International Journal of Stroke, April 3, 2013
17 Inhaled Sevoflurane May Promote Progression of Amnestic Mild Cognitive Impairment: A Prospective, Randomized Parallel-Group Study The American Journal of the Medical Sciences, April 23, 2013
18 Coronary Artery Calcification Is an Independent Stroke Predictor in the General Population Stroke, April 5, 2013
19 Long-term Mortality After Stroke Among Adults Aged 18 to 50 Years JAMA, April 12, 2013
20 The obesity paradox in stroke: Lower mortality and lower risk of readmission for recurrent stroke in obese stroke patients International Journal of Stroke, March 22, 2013
Indexed Journals in Neurology: Current Opinion in Neurology, Stroke, Seizure, Cephalgia, Brain Injury more
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