1Evaluation of Tai Chi Yunshou exercises on community-based stroke patients with balance dysfunction: a study protocol of a cluster randomized controlled trialBMC Complementary and Alternative Medicine  Full Text  Clinical Article
2Alcohol consumption at midlife and risk of stroke during 43 years of follow-upStroke  Clinical Article
3A preliminary study of zonisamide monotherapy in de novo patients with early Parkinson’s diseaseNeurology and Clinical Neuroscience  Full Text  Clinical Article
4Vitamin D deficiency in Parkinson's disease patients with orthostatic hypotensionActa Neurologica Scandinavica  Clinical Article
5The great sleep recession: changes in sleep duration among US adolescents, 1991-2012Pediatrics  Clinical Article
6Prophylactic onabotulinumtoxinA for migraine with depressionInternational Journal of General Medicine  Full Text  Clinical Article
7Headache in traumatic brain injuries from blunt head traumaPediatrics  Clinical Article
8Ischaemic stroke or TIA in older subjects associated with impaired dynamic blood pressure control in the absence of severe large artery stenosisAge and Aging  Clinical Article
9Head injury and risk for Parkinson disease: Results from a Danish case-control studyNeurology®  Clinical Article
10Depressive symptoms and biomarkers of Alzheimer's disease in cognitively normal older adultsJournal of Alzheimer’s Disease  Clinical Article
1Myelin-maker: How an FDA-approved drug boosts myelin synthesisUniversity at Buffalo Health and Medicine News
2Time to "just say no" to behavior-calming drugs for Alzheimer patients? Experts say yesUniversity of Michigan Health System
3Marijuana: The allergen you never knew existedAmerican College of Allergy, Asthma and Immunology News
4Results challenge conventional wisdom about where the brain begins processing visual informationVanderbilt University Medical Center Research News
5Teenager with stroke symptoms actually had Lyme diseaseAmerican College of Emergency Physicians News
6Scripps Florida scientists find a defect responsible for memory impairment in agingScripps Research Institute News
7A new stem cell advanceHarvard Gazette - Health News
8Neuron groups, not single cells, maintain brain stabilityAmerican Friends of Tel Aviv University Medicine and Health News
9Alzheimer amyloid clumps found in young adult brainsNorthwestern Medicine News
10New care model enhances psychological, cognitive and physical recovery of ICU survivorsIndiana University School of Medicine News

Show Me:

L-carnitine levels have clinical significance in non-APOE4 carriers with mild AD

As reported in the Journal of Alzheimer’s Disease, the CSF L-carnitine levels are decreased in patients with early Alzheimer’s disease (AD) who are non-APOE4 carriers. Further, the L-carnitine levels are correlated with Aβ42 and the MMSE score. It is suggested that L-carnitine supplementation may be beneficial in non-APOE4 carriers with mild AD.

Moderate exercise has a positive effect on DPN

As reported in Diabetes and Its Complications, moderate exercise (40%-60% heart rate reserve) for 8 weeks resulted in significant improvement in nerve conduction velocity (peroneal and sural nerves) in patients with T2DM and clinical neuropathy (n=87) as compared with standard care.

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Clinical Pearls

Clinical Pearl from Smartest DocSleep bruxism is associated with increased headache risk in adults.

Clinical Pearl from Smartest DocHypercholesterolemia and moderate alcohol use are not significantly associated with ICH.

Clinical Pearl from Smartest DocVitamin E treatment is associated with slowed functional decline in Alzheimer’s disease patients.

The Top Read Articles of 2014 are Now Available

Scouring thousands of peer-reviewed journals and popular press, Our Editors just released the Top Read Articles of the Year. See the Top Read List