Maternal hypertension and intrapartum fever are associated with increased risk of ischemic stroke during infancy
Developmental Medicine & Child Neurology,  Clinical Article

Mann JR et al. – Maternal hypertension and intrapartum fever appear to be risk factors for ischemic stroke in infants. Additional research is needed to determine the mechanism(s) underlying these associations and to develop effective preventive methods for high–risk infants.

Methods

  • The authors conducted a retrospective cohort study of 226 117 children born from January 2000 to December 2007 who were enrolled in the South Carolina Medicaid program.
  • They linked maternal and child Medicaid billing records and birth certificate data.
  • Children with ischemic stroke were identified based on the International Classification of Diseases, Ninth Revision (ICD-9), code 434 in the child’s billing data.
  • Independent variables and covariates were identified using ICD-9 codes and birth certificate data.
  • They modeled the odds of ischemic stroke diagnosis in infants, either before 30 days of life or before 365 days.

Results

  • Forty-three children were diagnosed with ischemic stroke before 30 days and 161 before 365 days.
  • Maternal hypertension (odds ratio 2.31 before 30d) and intrapartum fever (odds ratio 3.36 <30d) were significantly associated with odds of ischemic stroke before 30 days and before 365 days; maternal diabetes was not.

Please login or register to follow this author.
Are you sure you want to Unfollow this Author?
► Click here to access PubMed, Publisher and related articles...
<< Previous Article | Next Article >>

Your Unread Messages in Neurology

See All >> Messages include industry-sponsored communications and special communications from MDLinx

Most Popular Neurology Articles

1 Zolpidem and the risk of Parkinson's disease: A nationwide population-based study Journal of Psychiatric Research, August 1, 2014    Clinical Article

2 Long-term outcomes after stenting versus endarterectomy for treatment of symptomatic carotid stenosis: the International Carotid Stenting Study (ICSS) randomised trial The Lancet, October 17, 2014    Evidence Based Medicine    Clinical Article
Exclusive Author Commentary

3 Safety and efficacy of ceftriaxone for amyotrophic lateral sclerosis: A multi-stage, randomised, double-blind, placebo-controlled trial The Lancet Neurology, October 9, 2014    Clinical Article

4 Recurrent stroke in the warfarin versus aspirin in reduced cardiac ejection fraction (WARCEF) trial Cerebrovascular Diseases, October 16, 2014    Clinical Article

5 Dairy products and the risk of stroke and coronary heart disease: the Rotterdam Study European Journal of Nutrition, October 14, 2014    Clinical Article

6 Hyperhomocysteinemia and risk of cognitive decline: a meta-analysis of prospective cohort studies European Neurology, October 17, 2014    Review Article

7 Intracranial hemorrhage risk with the new oral anticoagulants: A systematic review and meta-analysis Journal of Neurology, September 2, 2014    Evidence Based Medicine    Review Article

8 Patent foramen ovale closure versus medical therapy for stroke prevention: meta analysis of randomized trials and review of heterogeneity in meta analyses Canadian Journal of Cardiology, August 7, 2014    Evidence Based Medicine    Review Article    Clinical Article

9 Consumption of nuts and legumes and risk of stroke: a meta-analysis of prospective cohort studies Nutrition, Metabolism & Cardiovascular Diseases, July 28, 2014    Evidence Based Medicine    Clinical Article

10 Effects of long-term blood pressure lowering and dual antiplatelet treatment on cognitive function in patients with recent lacunar stroke: a secondary analysis from the SPS3 randomised trial The Lancet Neurology, October 27, 2014    Evidence Based Medicine    Clinical Article

11 Antiepileptics in migraine prophylaxis: An updated Cochrane review Cephalalgia, August 14, 2014    Clinical Article

12 The durability of endovascular coiling versus neurosurgical clipping of ruptured cerebral aneurysms: 18 year follow-up of the UK cohort of the International Subarachnoid Aneurysm Trial (ISAT) The Lancet, October 30, 2014    Evidence Based Medicine    Clinical Article

13 Circulating biomarkers of dairy fat and risk of incident stroke in US men and women in 2 large prospective cohorts American Journal of Clinical Nutrition, October 1, 2014    Clinical Article

14 Dabigatran and warfarin for secondary prevention of stroke in atrial fibrillation patients: A nationwide cohort study American Journal of Medicine, September 29, 2014    Clinical Article

15 Antiplatelet strategies for secondary prevention of stroke and TIA Current Atherosclerosis Reports, September 11, 2014    Review Article

16 Management of high-grade gliomas in the elderly Seminars in Radiation Oncology, October 6, 2014    Clinical Article

17 Higher risk of death and stroke in patients with persistent vs. paroxysmal atrial fibrillation: results from the ROCKET-AF Trial European Heart Journal, September 17, 2014    Clinical Article

18 Long-term outcomes after combined revascularization surgery in adult moyamoya disease Stroke, October 8, 2014    Evidence Based Medicine    Clinical Article

19 Oral anticoagulants for stroke prevention in atrial fibrillation Current Problems in Cardiology, September 23, 2014    Review Article

20 Potassium intake and risk of stroke in women with hypertension and nonhypertension in the women’s health initiative Stroke, September 24, 2014    Clinical Article

Indexed Journals in Neurology: Current Opinion in Neurology, Stroke, Seizure, Cephalgia, Brain Injurymore

Register now to view all the MDLinx contents (FREE)!

  • Stay current on the latest literature, research and clinical news
  • Get special communications and offers from MDLinx and our sponsors
  • Receive invitations to paid market research
View Samples and Register

Connect with us, stay current.

Receive the latest mecial news
updates for free via email

Sign up!

Subscribe to our free RSS feeds:

Get the latest news in your specialty automatically added to your newsreader or your personal My Yahoo!, Google, My MSN or My AOL page. Learn More

Close