Characterization of thorn-shaped astrocytes in white matter of temporal lobe in Alzheimer disease brains
Brain Pathology, 08/21/2012
Lopez–Gonzalez I et al. – The finding suggest that ubiquitin is not accumulated in Thorn–shaped astrocytes (TsA), and in situ end–labelling of nuclear DNA fragmentation shows absence of degeneration in TsA. These observations support the concept that tau lesions in neurons differ from those seen in TsA in Alzheimer disease (AD).