Faster onset of antimanic action with haloperidol compared to second-generation antipsychotics. A meta-analysis of randomized clinical trials in acute mania
European Neuropsychopharmacology, 08/03/2012
Goikolea JM et al. – Haloperidol shows a faster onset of antimanic action than second–generation antipsychotics. This difference may be related to D2 affinity. Haloperidol may be considered a treatment option in severely ill manic patients who require urgent relief of symptoms.