How Does Metabolic Syndrome Affect the Functional Ambulation in Stroke Patients
Topics in Stroke Rehabilitation, 07/11/2012
Akbal A et al. – Metabolic syndrome (MetS) is associated with worse functional ambulation for both ischemic and hemorrhagic stroke patients. Aggressive rehabilitation can be advocated in the presence of MetS in ischemic stroke patients.Methods
- A total of 337 consecutive patients with subacute stroke and 220 age–matched healthy controls were studied.
- The diagnosis of MetS was based on the criteria of the National Cholesterol Education Program Adult Treatment Panel III.
- Ambulation levels were evaluated using the Functional Ambulation Classification (FAC) measure.
- The correlation between MetS and FAC was investigated.
- The regression analysis included presence of hypertriglyceridemia, high fasting glucose, low high–density lipoprotein cholesterol, hypertension, abdominal obesity, MetS, and age >65 years.
- The prevalence of MetS in the control group and the ischemic and hemorrhagic stroke groups was 33.2% (n = 73), 59.8% (n = 156), and 68.4% (n = 52), respectively.
- MetS prevalence was significantly higher in stroke groups compared with the control group (P < .001).
- FAC and MetS were significantly and negatively correlated in the stroke groups (P < .001, rho = –0.387, for hemorrhagic stroke;P < .001, rho = –0.379, for ischemic stroke).
- Multivariable logistic regression analysis demonstrated that diastolic tension, MetS presence, and age were found to be independent risk factors for FAC in ischemic stroke groups.