High Salt Intake and Stroke
CNS Neuroscience & Therapeutics, 07/16/2012
Evidence Based Medicine
Li XY et al. – High salt intake is associated with significantly increased risk of stroke event.Methods
- The review evaluated the current level of epidemiologic evidence on the association between the level of habitual salt intake and stroke outcome.
- There were 21 independent samples from 12 studies, with 225,693 participants (follow–up, 3–19 years) and 8135 stroke events.
- High salt intake was associated with risk of stroke event (pooled odd ratio [OR], 1.34; 95% confidence interval [CI], 1.19–1.51), stroke death (1.40; 1.21–1.63) and stroke onset (1.11; 1.00–1.24), ischemic stroke death (2.15; 1.57–2.95), not associated with risk of ischemic stroke onset (1.07, 0.95–1.2), with no significant evidence of publication bias.
- High salt intake is associated with significantly increased risk of stroke event.