Cortical interneurons, immune factors and oxidative stress as early targets for schizophrenia
European Journal of Neuroscience, 06/26/2012
O’Donnell P – The author review the developmental trajectory of the cortical circuits responsible for excitation–inhibition balance, which are at the center of current pathophysiological views, and propose that oxidative stress in cortical interneurons may be a final common pathway by which several different etiological factors can yield the cortical dysfunction characteristic of schizophrenia.
