Prospective Evaluation of 18F-NaF and 18F-FDG PET/CT in Detection of Occult Metastatic Disease in Biochemical Recurrence of Prostate Cancer

Clinical Nuclear Medicine , 06/13/2012

In biochemical relapse of prostate cancer, 18F–NaF PET/CT is useful in the detection of occult osseous metastases, whereas the yield of 18F–FDG PET/CT is relatively limited. 18F–NaF PET/CT positivity tends to associate with increasing prostate–specific antigen (PSA) level in prostatectomized men and may occur in lower PSA ranges than conventionally recognized.

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