Stroke risk and migraine: near-infrared spectroscopy study
Neurological Sciences, 06/18/2012
Viola S et al. - The study seems to indicate that the migraine is independently associated with a mild vasoconstriction of cerebral arterioles that may represent one possible mechanism underlying the increased stroke risk especially in patients with migraine with (MA+).Methods
- The authors studied 10 patients with MA+ (age 39.5 ± 12.2 years), 10 with MA- (age 40.3 ± 10.2 years), according to ICHD-II criteria 2004, during the interictal period of migraine, and 15 age- and sex-matched healthy control subjects.
- At rest in all the participants, the time-delay in millisecond (ms), between the R-wave of an electrocardiogram and the arterial pulse wave of cerebral microcirculation detected by transcranial near-infrared spectroscopy (R-APWCMtd) on the frontal cortex of both side, was determined to evaluate the presence of cerebral arteriolar vasoconstriction.
- The patients with migraine had a significantly longer R-APWCMtd than the control subjects: the patients with MA+: +38.3 ms, p < 0.0002; the patients with MA-: +34.7 ms, p < 0.0002.