Is alpha-synuclein in the colon a biomarker for premotor Parkinsons Disease- Evidence from 3 cases
Movement Disorders, 05/16/2012
Shannon KM et al. – This is the first demonstration of alpha–synuclein in colon tissue prior to onset of Parkinson's disease (PD). Additional study is required to determine whether colonic mucosal biopsy may be a biomarker of premotor PD.