Outcome After Surgery Alone or With Restricted Use of Chemotherapy for Patients With Low-Risk Neuroblastoma
Journal of Clinical Oncology, 04/26/2012
Strother DR et al. – Excellent survival rates can be achieved in asymptomatic low–risk patients with stages 2a and 2b neuroblastoma (NBL) after surgery alone. Immediate use of chemotherapy may be restricted to a minority of patients with low–risk NBL. Patients with stage 2b disease who are older or have diploid or unfavorable histology tumors fare less well. Future studies will seek to refine risk classification.