Pilates based core stability training in ambulant individuals with multiple sclerosis: Protocol for a multi-centre randomised controlled trial Full Text
BMC Neurology,  Clinical Article

Freeman JA et al. – The pragmatic trial will assess the effect of these exercise programmes on ambulatory people with Multiple Sclerosis (MS). It may not be possible to extrapolate the conclusions to those who are non–ambulatory.

Methods
  • This is a multi-centre, double blind, block randomised, controlled trial.
  • Eligible participants will be recruited from 4 UK centres.
  • Participants will be randomly allocated to one of three groups: Pilates based core stability training, standardised physiotherapy exercise or contract-relax relaxation sessions (placebo control).
  • All will receive face to face training sessions over a 12 week period; together with a 15 minute daily home programme.
  • All will be assessed by a blinded assessor before training, at the end of the 12 week programme and at 4 week follow-up.

Results
  • The primary outcome measure is the 10 metre timed walk.
  • Secondary outcome measures are the MS walking Scale (MSWS-12), the Functional Reach (forwards and lateral), a 10 point Numerical Rating Scale to determine "Difficulty in carrying a drink when walking", and the Activities-specific Balance Confidence (ABC) Scale.
  • In addition, ultrasound imaging of the abdominal muscles will be performed before and after intervention to assess changes in abdominal musculature at one of the four centres (Plymouth).

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