Pilot study of the efficacy and safety of lettuce seed oil in patients with sleep disorders Full Text
International Journal of General Medicine, 06/16/2011
Yakoot M et al. – L. sativa seed oil was found to be a useful sleeping aid and may be a hazard–free line of treatment, especially in geriatric patients suffering from mild–to–moderate forms of anxiety and sleeping difficulties.Methods
- Sixty patients suffering from insomnia with or without anxiety were randomized to receive capsules containing L. sativa seed oil 1000 mg (n = 30) or placebo (n = 30).
- All patients were asked to complete a verbal questionnaire before the start of the trial and 1 week after starting treatment.
- Improvements in the modified State–Trait Anxiety Inventory and the Sleep rating scale scores were significantly greater in patients receiving L. sativa seed oil compared with those on placebo (P < 0.05).
- No side effects were found to be attributable to L. sativa seed oil at the given dosage.