Directly observed treatment, short course in tuberculous meningitis: Indian perspective
Annals of the Indian Academy of Neurology, 03/01/2013Sharma SR et al.
The authors did a prospective study to assess effectiveness of Revised National TB Control Program (RNTCP–DOTS) regimes among tuberculous meningitis (TBM) patients. The authors found intermitted short course chemotherapy was effective in TBM.
In this study the authors include the TBM patients admitted from September 2008 to March 2011.
All were referred to RNTCP for treatment.
Diagnostic Algorithm as per RNTCP guidelines was strictly followed and treatment outcome and follow-up status were recorded.
The authors exclude HIV and pediatric age group.
A total of 42 cases registered for DOTS regimen were included in the study, of which 35 completed the treatment (83%).
All the patients were started with DOTS but finally 78% received actual DOTS.
All patients were given 9 months intermitted regimen as per RNTCP guidelines.
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