Subject movement during multislice interleaved MR acquisitions: Prevalence and potential effect on MRI-derived brain pathology measurements and multicenter clinical trials of therapeutics for multiple sclerosis

Journal of Magnetic Resonance Imaging, 05/14/2012

Inter–packet motion can introduce substantial errors to magnetic resonance imaging (MRI)–derived brain pathology measurements. The prevalence of inter–packet motion is substantial in multiple sclerosis (MS) clinical trial data. Automated detection procedures should be implemented to increase the fidelity of MRI–derived measurements.

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