Copper compound induces autophagy and apoptosis of glioma cells by reactive oxygen species and jnk activation

BMC Cancer, 05/11/2012

The data suggest that Cas III–ia induces cell death by autophagy and apoptosis, in part due to the activation of ROS –dependent JNK signaling. These findings support further studies of Cas III–ia as candidate for treatment of human malignant glioma.

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