Pre- and post-operative plasma glial fibrillary acidic protein levels in patients with newly diagnosed gliomas

Journal of Neuro-Oncology, 04/30/2012

Higher plasma GFAP (pGFAP) concentrations were also associated with contrast enhancement but not related to tumor glial fibrillary acidic protein (GFAP) expression. GFAP is commonly detected in the plasma of patients with high–grade gliomas. pGFAP levels rise rather than fall following debulking surgery which is probably a result of surgical trauma. GFAP remains a potentially informative plasma biomarker for gliomas.

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