Moderate exercise has a positive effect on DPN
As reported in Diabetes and Its Complications, moderate exercise (40%-60% heart rate reserve) for 8 weeks resulted in significant improvement in nerve conduction velocity (peroneal and sural nerves) in patients with T2DM and clinical neuropathy (n=87) as compared with standard care.
L-carnitine levels have clinical significance in non-APOE4 carriers with mild AD
As reported in the Journal of Alzheimers Disease, the CSF L-carnitine levels are decreased in patients with early Alzheimers disease (AD) who are non-APOE4 carriers. Further, the L-carnitine levels are correlated with Aβ42 and the MMSE score. It is suggested that L-carnitine supplementation may be beneficial in non-APOE4 carriers with mild AD.